Biography
In his research, Corvera focuses on the mechanisms that underlie inflammation, thickening and scarring in the biliary tract.
Corvera graduated from the University of California, San Diego School of Medicine. He completed a residency in general surgery at UCSF. At Memorial Sloan Kettering Cancer Center in New York City, he completed a clinical fellowship in surgical oncology as well as a fellowship in hepatobiliary surgery.
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Education
Institution | Degree | Dept or School | End Date |
---|---|---|---|
Memorial Sloan Kettering Cancer Center, New York | Hepatobiliary Surgery | Surgery | 2002 |
Memorial Sloan Kettering Cancer Center , New York | Surgical Oncology Clinical Fellowship | Surgery | 2001 |
University of California, San Francisco | General Surgery Residency | School of Medicine | 2000 |
University of California San Diego | M.D. | School of Medicine | 1993 |
Board Certifications
- American Board of Surgery
Clinical Expertise
Ascites
Bile Duct Injuries
Bile Duct Strictures
Bile Duct Cancer (Cholangiocarcinoma)
Gastrointestinal Carcinoid Tumor
Gastrointestinal Stromal Tumor (GIST)
Choledochal Cysts
Portal Hypertension
Liver Cancer (Hepatocellular Carcinoma)
Minimally Invasive Liver & Pancreas Surgery
Melanoma
Pancreatic Cancer
Pancreatic Cysts
Soft Tissue Sarcomas
Liver Cysts
Liver Metastases
Gallbladder Cancer
Stomach (Gastric) Cancer
Pancreatic Neuroendocrine (Islet Cell) Tumors
Bridging Therapies to Downstage HCC in Setting of Liver Transplantation
Program Affiliations
Hepatobiliary and Pancreas Surgery Program
UCSF Helen Diller Family Comprehensive Cancer Center
UCSF Department of Surgery at the San Francisco VA
In the News
Research Narrative
Dr. Corvera's scientific research interest is focused on understanding the mechanisms of biliary tract fibrosis and inflammation. More specifically, he is interested in studying the clinical consequences of biliary fibrosis-- mainly cholestatisis. Cholestasis is characterized by impaired bile flow causing a high concentration of bile acids in the liver and the circulation. Prolonged exposure to bile acids in the liver can progress to end-stage liver disease and cirrhosis. In the gastrointestinal tract, the absence of bile flow causes profound local and systemic metabolic disturbances. Dr.Corvera is actively investigating the role of a novel cell surface receptor specific for bile acids that may play a critical role in normal and disease states.
Research Interests
Proteases and Proteinase Activated Receptors in the Biliary Tract
Publications
- Minimal Residual Disease using a Plasma-Only Circulating Tumor DNA Assay to Predict Recurrence of Metastatic Colorectal Cancer Following Curative Intent Treatment.| | PubMed
- Long-Duration Neoadjuvant Therapy with FOLFIRINOX Yields Favorable Outcomes for Patients Who Undergo Surgery for Pancreatic Cancer.| | PubMed
- Long-Term Survival Outcomes After Minimally Invasive Surgery for Ileal Neuroendocrine Tumors.| | PubMed
- National practice patterns in the use of endoscopic ultrasound biopsy for resectable Pancreatic Neuroendocrine Tumors: Insights into the role of DOTATATE PET/CT in diagnosis.| | PubMed
- Recurrence and tumor-related death after resection of hepatocellular carcinoma in patients with metabolic syndrome.| | PubMed
- Metastatic melanoma to small bowel: metastasectomy is supported in the era of immunotherapy and checkpoint inhibitors.| | PubMed
- Portal Vein Thrombosis After Transarterial Embolization for Hepatocellular Carcinoma.| | PubMed
- Intraoperative hepatic artery infusion pump perfusion testing with indocyanine green near-infrared imaging offers multiple potential advantages.| | PubMed
- Improved survival of patients receiving immunotherapy and chemotherapy following curative-intent resection of colorectal liver metastases.| | PubMed
- A Machine Learning Approach to Predict Postoperative Pancreatic Fistula After Pancreaticoduodenectomy Using Only Preoperatively Known Data.| | PubMed