University of California San Francisco

Chris E. Freise
Chris
Freise
MD, FACS

Professor of Surgery 
Chief, Division of Transplant Surgery

UCSF Diversity, Equity, and Inclusion Champion badge

Address

35 Medical Center Way, #001
San Francisco, CA 94143
United States

Email: [email protected]
Phone: 415-353-1898
Fax: 415-476-8709

    Biography

    Chris E. Freise, M.D. received his medical degree from the University of Minnesota where he also did his internship and residency in General Surgery. He later completed a  transplantation fellowship at UCSF.   

    He is a member of numerous professional organizations including The Transplantation Society, the International Pancreas and Islet Transplant Association, the Transplant Infectious Disease Society, the American Hepato-Pancreato-Billiary Association and the Society of University Surgeons. In addition, he recently served as the Medical Director for California Transplant Donor Network. He is also the Associate Counselor for UNOS Region 5, and a member of the UNOS Membership and Professional Standards Committee.

    Dr. Freise has authored more than eighty (80) in peer-reviewed publications and five (5) book chapters. He is an accomplished researcher and clinical educator. Dr. Freise is also a frequent invited lecturer to national and international and conferences in the field.         

    Education

    Institution Degree Dept or School End Date
    University of California Diversity, Equity, and Inclusion Champion Training 2019
    University of California, San Francisco Transplant Fellowship School of Medicine 1995
    University of California, San Francisco Post-Doc Fellow/Scholar School of Medicine 1991
    University of Minnesota M.D. School of Medicine 1986

    Board Certifications

    • American Board of Surgery, 1995

    Clinical Expertise

    Bile Duct Injuries
    Bile Duct Strictures
    Cholangiocarcinoma (Bile Duct Cancer)
    Choledochal Cyst Disease
    Dialysis Access
    Expanded Criteria Donor Kidney Transplantation
    Fulminant Hepatic Failure
    Hepatitis B
    Hepatitis C
    Hepatocellular Carcinoma (Liver Cancer)
    Intestinal Transplantation and Rehabilitation
    Kidney and LIver Transplantation in HIV Patients
    Kidney Auto-transplantation
    Kidney Transplantation
    Laparoscopic Donor Nephrectomy
    Laparoscopic Kidney and Liver Surgery
    Liver Transplantation
    Living Donor Kidney Transplantation
    Living Donor Liver Transplantation
    Pancreas Transplantation
    Pediatric Kidney Transplantation
    Pediatric Liver Transplantation
    Polycystic Kidney Disease
    Polycystic Liver Disease
    Portal Hypertension
    Surgical Shunts

    Grants and Funding

    • Living Donor Liver Transplant :Short & Long-Term Impact on Donors and Recipients | NIH | 2002-09-01 - 2015-08-31 | Role: Principal Investigator

    Research Narrative

    Dr. Friese's basic science research focuses on the delivery of immunosuppressive agents to organ allografts, ischemia reperfusion injury, and methods to improve organ function in deceased donors. His clinical research includes  a multicenter trial investigating donor and recipient outcomes following living donor liver transplantation.

    Research Interests

    Delivery of Immunosuppressive Agents to Organ Allografts

    Ischemia Reperfusion Injury

    Improvement Organ Function in Deceased Donors

    Publications

    MOST RECENT PUBLICATIONS FROM A TOTAL OF 125
    1. Sclerosing peritonitis.
      Meng MV, Freise CE, Stoller ML| | PubMed
    2. Expanded experience with laparoscopic nephrectomy and autotransplantation for severe ureteral injury.
      Meng MV, Freise CE, Stoller ML| | PubMed
    3. Techniques to optimize vascular control during laparoscopic donor nephrectomy.
      Meng MV, Freise CE, Kang SM, Duh QY, Stoller ML| | PubMed
    4. Anti-lymphocyte function-associated antigen-1 monoclonal antibody inhibits CD40 ligand-independent immune responses and prevents chronic vasculopathy in CD40 ligand-deficient mice.
      Corbascio M, Mahanty H, Osterholm C, Qi Z, Pearson TC, Larsen CP, Freise CE, Ekberg H| | PubMed
    5. Successful long-term outcomes using pediatric en bloc kidneys for transplantation.
      Hiramoto JS, Freise CE, Randall HR, Bretan PN, Tomlanovich S, Stock PG, Hirose R| | PubMed
    6. Laparoscopic nephrectomy and autotransplantation for severe iatrogenic ureteral injuries.
      Shekarriz B, Lu H, Duh Q, Freise CE, Stoller ML| | PubMed
    7. A calcineurin inhibitor-sparing regimen with sirolimus, mycophenolate mofetil, and anti-CD25 mAb provides effective immunosuppression in kidney transplant recipients with delayed or impaired graft function.
      Chang GJ, Mahanty HD, Vincenti F, Freise CE, Roberts JP, Ascher NL, Stock PG, Hirose R| | PubMed
    8. Experience with the use of sirolimus in liver transplantation--use in patients for whom calcineurin inhibitors are contraindicated.
      Chang GJ, Mahanty HD, Quan D, Freise CE, Ascher NL, Roberts JP, Stock PG, Hirose R| | PubMed
    9. Prolonged cold ischemia time obviates the benefits of 0 HLA mismatches in renal transplantation.
      Lee CM, Carter JT, Alfrey EJ, Ascher NL, Roberts JP, Freise CE| | PubMed
    10. The effect of age and prolonged cold ischemia times on the national allocation of cadaveric renal allografts.
      Lee CM, Carter JT, Randall HB, Hiose R, Stock PG, Melzer JS, Dafoe DC, Freise CE, Alfrey EJ| | PubMed