Biography
In addition I have advanced training in the interventional pulmonary techniques utilized to diagnose and treat malignant and benign processes in the trachea and bronchi. These techniques include rigid bronchoscopy, bronchial and tracheal stent placement, as well as cryoablative techniques including cryospray and cryoprobe ablation. I am also a co-investigator on several industry sponsored trials of lung volume reduction of emphysema through endobronchial coil or valve placement.
Procedures Performed:
* endobronchial ultrasound (EBUS)
* electromagnetic navigation bronchoscopy (EMN)
* gold fiducial placement
* rigid bronchoscopy
* cryospray ablation
* Argon Plasma Coagulation
* foreign body removal from the airway
* balloon dilation of the airway (balloon bronchoplasty)
* endobronchial stent placement
* Endobronchial valve placement for bronchopleural fistulae
Disease Treated
* lung nodule/mass diagnostics
* hilar and mediastinal lymph node biopsies
* carcinoid tumors
* Lung Cancer
* tracheobronchomalacia
* relapsing polychondritis
* Wegner's Granulomatosis
In order to schedule an appointment to see me in the Interventional Pulmonary clinic at UCSF please call the number above (415-353-7285). During all clinical consultations, it is essential that you bring a disk with a copy of all outside chest CTs or PET scans.
In addition to specializing in pulmonary procedures, I am also an attending in the UCSF medical and surgical intensive care units where I manage critically ill patients with respiratory failure and septic shock. I have done research on sepsis and the acute respiratory distress syndrome and am the course director for the critical care ultrasound course at UCSF.
Awards & Honors
Award | Conferred By | Date |
---|---|---|
Best Abstract Sepsis 2012 | International Sepsis Meeting | 2012 |
Professionalism Award | UCSF | 2007 |
Resident teaching award | UCSF | 2007 |
Education
Institution | Degree | Dept or School | End Date |
---|---|---|---|
UCSF/PAMF | Fellowship in Interventional Pulmonary Medicine | Internal Medicine | 2014 |
UCSF | Fellowship in Pulmonary and Critical Care | Internal Medicine | 2010 |
UCSF | Residency | Internal Medicine | 2006 |
University of Chicago | M.D. | School of Medicine | 2003 |
Northwestern University | B.S. Biomedical Engineering | School of Engineering | 1997 |
Board Certifications
American Board of Internal Medicine,
Internal Medicine - General
Critical Care Medicine - Subspecialty
Pulmonary Disease - Subspecialty
Clinical Expertise
Argon Plasma Coagulation (APC) therapy for bleeding or tumor invasion
Carcinoid Tumors
Complex Pleural Effusions
Cryo-probe resection of airway tumors
Cryospray Ablation of Airway Tumors
Electromagnetic Navigation Bronchoscopy (EMN)
Endobronchial Ultrasound guided Bronchoscopy (EBUS)
Enlarged Lymph Nodes In The Chest
Gold and Platinum Fiducial Placement for Radiation Therapy
Lung Cancer Diagnostics And Staging
Lung Masses
Sarcoidosis
Tracheal And Bronchial Obstructions
Tracheal and Bronchial Stent Placement
Grants and Funding
- Regulation of Innate Immunity by the Sympathetic Nervous System Druing Sepsis | NIH | 2012-08-01 - 2017-05-31 | Role: Principal Investigator
Research Narrative
My research lies at the intersection of the nervous system and immunity. Specifically, I have been studying how noradrenergic neurons influence the immune response during severe infection in mice. These studies may have important implications for how states of heightened stress, that lead to elevations in systemic catecholamines, alter the immune system. A second area of research is the epigenetic imprint of severe sepsis on human monocytes.
Research Interests
Sepsis
ARDS
Mechanical Ventilations
Lung Cancer Diagnostics
New Techniques in Interventional Pulmonary Medicine
Publications
- Safety and utility of indwelling pleural catheters in lung transplant recipients.| | PubMed
- Impact of a Dedicated Pleural Clinic on Indwelling Pleural Catheter Related Outcomes: A Retrospective Single Center Experience.| | PubMed
- Therapeutic Bronchoscopy: Beyond Just Relieving the Obstruction.| | PubMed
- Lung Cancer Screening.| | PubMed
- A Woman with One Year of Cough Presumed to Be Asthma.| | PubMed
- A retrospective observational study of benign anthracotic lymphadenitis and its association with PET avid lymph nodes in patients undergoing cancer evaluation.| | PubMed
- Nonfibered Packing Coil Embolization of Pulmonary Artery Pseudoaneurysm Resulting in a Delayed Endobronchial Coil Migration.| | PubMed
- Molecular cytopathology diagnosis of a lung neoplasm: Case report of an unusual non-small cell carcinoma with MET exon 14 skipping mutation.| | PubMed
- Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing.| | PubMed
- Fluid Response Evaluation in Sepsis Hypotension and Shock: A Randomized Clinical Trial.| | PubMed
- Patient-controlled Anesthesia With Propofol During Bronchoscopy.| | PubMed
- Acute respiratory distress syndrome-attributable mortality in critically ill patients with sepsis.| | PubMed
- Flexible Bronchoscopic Deployment of a Silicone Bronchial Stent.| | PubMed
- Bilateral Endobronchial Masses and Severe Hypoxemic Respiratory Failure.| | PubMed
- Efforts to Limit Publication Bias and Improve Quality in the Journal: Introduction of Double-Blind Peer Review.| | PubMed
- The Impact of Bronchial Thermoplasty on Asthma-Related Quality of Life and Controller Medication Use.| | PubMed
- Using a Dedicated Interventional Pulmonology Practice Decreases Wait Time Before Treatment Initiation for New Lung Cancer Diagnoses.| | PubMed
- Central Airway Obstruction Due to Tracheal Glomus Tumor.| | PubMed
- Pulmonary Sclerosing Pneumocytoma: Did Lightening Just Strike Twice?| | PubMed
- A mass that has no (EBUS) echo.| | PubMed
- Endobronchial Ultrasound-guided Transbronchial Needle Injection of Liposomal Amphotericin B for the Treatment of Symptomatic Aspergilloma.| | PubMed
- Electromagnetic Navigational Bronchoscopy Spares a Drunken Crab From the Surgeon's Knife.| | PubMed
- Immune Repertoire Diversity Correlated with Mortality in Avian Influenza A (H7N9) Virus Infected Patients.| | PubMed
- Sepsis.| | PubMed
- Multiple gene mutations identified in patients infected with influenza A (H7N9) virus.| | PubMed
- Effect of Endobronchial Coils vs Usual Care on Exercise Tolerance in Patients With Severe Emphysema: The RENEW Randomized Clinical Trial.| | PubMed
- Therapeutic Targets in Sepsis: Past, Present, and Future.| | PubMed
- Fibroblast Growth Factor-10 (FGF-10) Mobilizes Lung-resident Mesenchymal Stem Cells and Protects Against Acute Lung Injury.| | PubMed
- Development and Validation of a Mortality Prediction Model for Patients Receiving 14 Days of Mechanical Ventilation.| | PubMed
- One-Way Valves to the Rescue for Bronchopleural Fistulae.| | PubMed
- Adipose Tissue-Derived Mesenchymal Stem Cells Attenuate Pulmonary Infection Caused by Pseudomonas aeruginosa via Inhibiting Overproduction of Prostaglandin E2.| | PubMed
- Increased expression of neutrophil-related genes in patients with early sepsis-induced ARDS.| | PubMed
- Fluid therapy during acute respiratory distress syndrome: less is more, simplified*.| | PubMed
- Acute respiratory distress syndrome: emerging research in China.| | PubMed
- A dry lung is a happy lung: more supporting evidence.| | PubMed
- From storm to suppression in sepsis: are bands the link?*.| | PubMed
- Increased susceptibility to Klebsiella pneumonia and mortality in GSNOR-deficient mice.| | PubMed
- Noradrenergic neurons regulate monocyte trafficking and mortality during gram-negative peritonitis in mice.| | PubMed
- Calcium flux and endothelial dysfunction during acute lung injury: a STIMulating target for therapy.| | PubMed
- Updates in the management of acute lung injury: a focus on the overlap between AKI and ARDS.| | PubMed
- Inflection points in sepsis biology: from local defense to systemic organ injury.| | PubMed
- A multicenter mortality prediction model for patients receiving prolonged mechanical ventilation.| | PubMed
- Parasitic infection improves survival from septic peritonitis by enhancing mast cell responses to bacteria in mice.| | PubMed
- Systemic mast cell degranulation increases mortality during polymicrobial septic peritonitis in mice.| | PubMed
- Decreased respiratory system compliance on the sixth day of mechanical ventilation is a predictor of death in patients with established acute lung injury.| | PubMed
- Predictors of mortality in acute lung injury during the era of lung protective ventilation.| | PubMed
- Diabetic ketoacidosis precipitated by Staphylococcus aureus abscess and bacteremia due to acupuncture: case report and review of the literature.| | PubMed