University of California San Francisco

Seeley Eric J
Eric J. Seeley, MD

Assistant Professor of Medicine,

Director of Bronchoscopy and Interventional Pulmonary Medicine

Fellowship Directory, Interventional Pulmonary Medicine

Division of Pulmonary & Critical Care Medicine

Department of Medicine

Address

521 Parnassus Avenue, #6227
San Francisco, CA 94117
United States

Email: [email protected]

Biography

I am a clinician who focuses on pulmonary procedures, including the advanced bronchoscopic techniques of endobronchial ultrasound (EBUS) and electromagnetic navigation bronchoscopy (EMN). In general, these are less invasive techniques frequently utilized to diagnose lung nodules, lung masses, mediastinal and hilar enlargement of lymph nodes and lung infections.

In addition I have advanced training in the interventional pulmonary techniques utilized to diagnose and treat malignant and benign processes in the trachea and bronchi. These techniques include rigid bronchoscopy, bronchial and tracheal stent placement, as well as cryoablative techniques including cryospray and cryoprobe ablation. I am also a co-investigator on several industry sponsored trials of lung volume reduction of emphysema through endobronchial coil or valve placement.

Procedures Performed:
* endobronchial ultrasound (EBUS)
* electromagnetic navigation bronchoscopy (EMN)
* gold fiducial placement
* rigid bronchoscopy
* cryospray ablation
* Argon Plasma Coagulation
* foreign body removal from the airway
* balloon dilation of the airway (balloon bronchoplasty)
* endobronchial stent placement
* Endobronchial valve placement for bronchopleural fistulae

Disease Treated
* lung nodule/mass diagnostics
* hilar and mediastinal lymph node biopsies
* carcinoid tumors
* Lung Cancer
* tracheobronchomalacia
* relapsing polychondritis
* Wegner's Granulomatosis

In order to schedule an appointment to see me in the Interventional Pulmonary clinic at UCSF please call the number above (415-353-7285). During all clinical consultations, it is essential that you bring a disk with a copy of all outside chest CTs or PET scans.

In addition to specializing in pulmonary procedures, I am also an attending in the UCSF medical and surgical intensive care units where I manage critically ill patients with respiratory failure and septic shock. I have done research on sepsis and the acute respiratory distress syndrome and am the course director for the critical care ultrasound course at UCSF.

Education

Institution Degree Dept or School End Date
UCSF/PAMF Fellowship in Interventional Pulmonary Medicine Internal Medicine 2014
UCSF Fellowship in Pulmonary and Critical Care Internal Medicine 2010
UCSF Residency Internal Medicine 2006
University of Chicago M.D. School of Medicine 2003
Northwestern University B.S. Biomedical Engineering School of Engineering 1997

Board Certifications

American Board of Internal Medicine,
Internal Medicine - General
Critical Care Medicine - Subspecialty
Pulmonary Disease - Subspecialty

Awards & Honors

Award Conferred By Date
Best Abstract Sepsis 2012 International Sepsis Meeting 2012
Professionalism Award UCSF 2007
Resident teaching award UCSF 2007

Clinical Expertise

Argon Plasma Coagulation (APC) therapy for bleeding or tumor invasion

Carcinoid Tumors

Complex Pleural Effusions

Cryo-probe resection of airway tumors

Cryospray Ablation of Airway Tumors

Electromagnetic Navigation Bronchoscopy (EMN)

Endobronchial Ultrasound guided Bronchoscopy (EBUS)

Enlarged Lymph Nodes In The Chest

Gold and Platinum Fiducial Placement for Radiation Therapy

Lung Cancer Diagnostics And Staging

Lung Masses

Sarcoidosis

Tracheal And Bronchial Obstructions 

Tracheal and Bronchial Stent Placement

Grants and Funding

  • Regulation of Innate Immunity by the Sympathetic Nervous System Druing Sepsis | NIH | 2012-08-01 - 2017-05-31 | Role: Principal Investigator

Research Narrative

My research lies at the intersection of the nervous system and immunity. Specifically, I have been studying how noradrenergic neurons influence the immune response during severe infection in mice. These studies may have important implications for how states of heightened stress, that lead to elevations in systemic catecholamines, alter the immune system. A second area of research is the epigenetic imprint of severe sepsis on human monocytes.

Research Interests

Sepsis

ARDS

Mechanical Ventilations

Lung Cancer Diagnostics

New Techniques in Interventional Pulmonary Medicine

Publications

MOST RECENT PUBLICATIONS FROM A TOTAL OF 47
  1. Adipose Tissue-Derived Mesenchymal Stem Cells Attenuate Pulmonary Infection Caused by Pseudomonas aeruginosa via Inhibiting Overproduction of Prostaglandin E2.
    Mao YX, Xu JF, Seeley EJ, Tang XD, Xu LL, Zhu YG, Song YL, Qu JM| | PubMed
  2. Increased expression of neutrophil-related genes in patients with early sepsis-induced ARDS.
    Kangelaris KN, Prakash A, Liu KD, Aouizerat B, Woodruff PG, Erle DJ, Rogers A, Seeley EJ, Chu J, Liu T, Osterberg-Deiss T, Zhuo H, Matthay MA, Calfee CS| | PubMed
  3. Fluid therapy during acute respiratory distress syndrome: less is more, simplified*.
    Seeley EJ| | PubMed
  4. Acute respiratory distress syndrome: emerging research in China.
    Song Y, Xu F, Seeley EJ, Ou J, Zhu X, Sun R, Bai C| | PubMed
  5. A dry lung is a happy lung: more supporting evidence.
    Seeley EJ| | PubMed
  6. From storm to suppression in sepsis: are bands the link?*.
    Kangelaris KN, Seeley EJ| | PubMed
  7. Increased susceptibility to Klebsiella pneumonia and mortality in GSNOR-deficient mice.
    Tang CH, Seeley EJ, Huang X, Wolters PJ, Liu L| | PubMed
  8. Noradrenergic neurons regulate monocyte trafficking and mortality during gram-negative peritonitis in mice.
    Seeley EJ, Barry SS, Narala S, Matthay MA, Wolters PJ| | PubMed
  9. Calcium flux and endothelial dysfunction during acute lung injury: a STIMulating target for therapy.
    Seeley EJ, Rosenberg P, Matthay MA| | PubMed
  10. Updates in the management of acute lung injury: a focus on the overlap between AKI and ARDS.
    Seeley EJ| | PubMed
47
View all 47 Publications
MOST RECENT PUBLICATIONS FROM A TOTAL OF 47
  1. Safety and utility of indwelling pleural catheters in lung transplant recipients.
    Trindade AJ, Lentz RJ, Gannon WD, Rickman OB, Shojaee S, Vandervest K, Schwartz G, Li GW, Kumar A, Garcha PS, Seeley EJ, Gesthalter YB, Mueller S, Egan JP, DeMaio AJ, Yarmus LB, Josan ES, Pannu JK, Wayne MT, DeCardenas JL, Bacchetta MD, Maldonado F, Interventional Pulmonary Outcomes Group| | PubMed
  2. Impact of a Dedicated Pleural Clinic on Indwelling Pleural Catheter Related Outcomes: A Retrospective Single Center Experience.
    Malcolm KB, Seeley EJ, Gesthalter YB| | PubMed
  3. Therapeutic Bronchoscopy: Beyond Just Relieving the Obstruction.
    Yu EA, Seeley EJ| | PubMed
  4. Lung Cancer Screening.
    Gesthalter YB, Seeley EJ| | PubMed
  5. A Woman with One Year of Cough Presumed to Be Asthma.
    Leba CT, Seeley EJ, Bhakta NR, Block BL| | PubMed
  6. A retrospective observational study of benign anthracotic lymphadenitis and its association with PET avid lymph nodes in patients undergoing cancer evaluation.
    Ivanick NM, Shrestha P, Podolsky MJ, Walavalkar V, Lucas CH, Gesthalter YB, Seeley EJ| | PubMed
  7. Nonfibered Packing Coil Embolization of Pulmonary Artery Pseudoaneurysm Resulting in a Delayed Endobronchial Coil Migration.
    Schwertner A, Kohlbrenner RM, Seeley EJ, Lokken RP| | PubMed
  8. Molecular cytopathology diagnosis of a lung neoplasm: Case report of an unusual non-small cell carcinoma with MET exon 14 skipping mutation.
    Hosseini SM, Khanafshar E, Seeley EJ, Ruiz-Cordero R| | PubMed
  9. Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing.
    Maynard A, McCoach CE, Rotow JK, Harris L, Haderk F, Kerr DL, Yu EA, Schenk EL, Tan W, Zee A, Tan M, Gui P, Lea T, Wu W, Urisman A, Jones K, Sit R, Kolli PK, Seeley E, Gesthalter Y, Le DD, Yamauchi KA, Naeger DM, Bandyopadhyay S, Shah K, Cech L, Thomas NJ, Gupta A, Gonzalez M, Do H, Tan L, Bacaltos B, Gomez-Sjoberg R, Gubens M, Jahan T, Kratz JR, Jablons D, Neff N, Doebele RC, Weissman J, Blakely CM, Darmanis S, Bivona TG| | PubMed
  10. Fluid Response Evaluation in Sepsis Hypotension and Shock: A Randomized Clinical Trial.
    Douglas IS, Alapat PM, Corl KA, Exline MC, Forni LG, Holder AL, Kaufman DA, Khan A, Levy MM, Martin GS, Sahatjian JA, Seeley E, Self WH, Weingarten JA, Williams M, Hansell DM| | PubMed
  11. Patient-controlled Anesthesia With Propofol During Bronchoscopy.
    Seeley EJ| | PubMed
  12. Acute respiratory distress syndrome-attributable mortality in critically ill patients with sepsis.
    Auriemma CL, Zhuo H, Delucchi K, Deiss T, Liu T, Jauregui A, Ke S, Vessel K, Lippi M, Seeley E, Kangelaris KN, Gomez A, Hendrickson C, Liu KD, Matthay MA, Ware LB, Calfee CS| | PubMed
  13. Flexible Bronchoscopic Deployment of a Silicone Bronchial Stent.
    Gesthalter YB, Seeley EJ| | PubMed
  14. Bilateral Endobronchial Masses and Severe Hypoxemic Respiratory Failure.
    Ivanick NM, Moh M, Seeley EJ, Benn BS| | PubMed
  15. Efforts to Limit Publication Bias and Improve Quality in the Journal: Introduction of Double-Blind Peer Review.
    Ost DE, Seeley EJ, Shojaee S, Yasufuku K| | PubMed
  16. The Impact of Bronchial Thermoplasty on Asthma-Related Quality of Life and Controller Medication Use.
    Seeley EJ, Alshelli I, Canfield J, Lum M, Krishna G| | PubMed
  17. Using a Dedicated Interventional Pulmonology Practice Decreases Wait Time Before Treatment Initiation for New Lung Cancer Diagnoses.
    Benn BS, Parikh M, Tsau PH, Seeley E, Krishna G| | PubMed
  18. Central Airway Obstruction Due to Tracheal Glomus Tumor.
    Haro GJ, Seeley EJ, Jablons DM, Kratz JR| | PubMed
  19. Pulmonary Sclerosing Pneumocytoma: Did Lightening Just Strike Twice?
    Alshelli I, Seeley EJ| | PubMed
  20. A mass that has no (EBUS) echo.
    Rosenblum MK, Wang SX, Seeley EJ| | PubMed
  21. Endobronchial Ultrasound-guided Transbronchial Needle Injection of Liposomal Amphotericin B for the Treatment of Symptomatic Aspergilloma.
    Parikh MS, Seeley E, Nguyen-Tran E, Krishna G| | PubMed
  22. Electromagnetic Navigational Bronchoscopy Spares a Drunken Crab From the Surgeon's Knife.
    Parikh MS, Seeley E, Krishna G| | PubMed
  23. Immune Repertoire Diversity Correlated with Mortality in Avian Influenza A (H7N9) Virus Infected Patients.
    Hou D, Ying T, Wang L, Chen C, Lu S, Wang Q, Seeley E, Xu J, Xi X, Li T, Liu J, Tang X, Zhang Z, Zhou J, Bai C, Wang C, Byrne-Steele M, Qu J, Han J, Song Y| | PubMed
  24. Sepsis.
    Bastarache JA, Seeley EJ| | PubMed
  25. Multiple gene mutations identified in patients infected with influenza A (H7N9) virus.
    Chen C, Wang M, Zhu Z, Qu J, Xi X, Tang X, Lao X, Seeley E, Li T, Fan X, Du C, Wang Q, Yang L, Hu Y, Bai C, Zhang Z, Lu S, Song Y, Zhou W| | PubMed
  26. Effect of Endobronchial Coils vs Usual Care on Exercise Tolerance in Patients With Severe Emphysema: The RENEW Randomized Clinical Trial.
    Sciurba FC, Criner GJ, Strange C, Shah PL, Michaud G, Connolly TA, Deslée G, Tillis WP, Delage A, Marquette CH, Krishna G, Kalhan R, Ferguson JS, Jantz M, Maldonado F, McKenna R, Majid A, Rai N, Gay S, Dransfield MT, Angel L, Maxfield R, Herth FJ, Wahidi MM, Mehta A, Slebos DJ, RENEW Study Research Group| | PubMed
  27. Therapeutic Targets in Sepsis: Past, Present, and Future.
    Seeley EJ, Bernard GR| | PubMed
  28. Fibroblast Growth Factor-10 (FGF-10) Mobilizes Lung-resident Mesenchymal Stem Cells and Protects Against Acute Lung Injury.
    Tong L, Zhou J, Rong L, Seeley EJ, Pan J, Zhu X, Liu J, Wang Q, Tang X, Qu J, Bai C, Song Y| | PubMed
  29. Development and Validation of a Mortality Prediction Model for Patients Receiving 14 Days of Mechanical Ventilation.
    Hough CL, Caldwell ES, Cox CE, Douglas IS, Kahn JM, White DB, Seeley EJ, Bangdiwala SI, Rubenfeld GD, Angus DC, Carson SS, ProVent Investigators and the National Heart Lung and Blood Institute’s Acute Respiratory Distress S| | PubMed
  30. One-Way Valves to the Rescue for Bronchopleural Fistulae.
    Seeley EJ| | PubMed
  31. Adipose Tissue-Derived Mesenchymal Stem Cells Attenuate Pulmonary Infection Caused by Pseudomonas aeruginosa via Inhibiting Overproduction of Prostaglandin E2.
    Mao YX, Xu JF, Seeley EJ, Tang XD, Xu LL, Zhu YG, Song YL, Qu JM| | PubMed
  32. Increased expression of neutrophil-related genes in patients with early sepsis-induced ARDS.
    Kangelaris KN, Prakash A, Liu KD, Aouizerat B, Woodruff PG, Erle DJ, Rogers A, Seeley EJ, Chu J, Liu T, Osterberg-Deiss T, Zhuo H, Matthay MA, Calfee CS| | PubMed
  33. Fluid therapy during acute respiratory distress syndrome: less is more, simplified*.
    Seeley EJ| | PubMed
  34. Acute respiratory distress syndrome: emerging research in China.
    Song Y, Xu F, Seeley EJ, Ou J, Zhu X, Sun R, Bai C| | PubMed
  35. A dry lung is a happy lung: more supporting evidence.
    Seeley EJ| | PubMed
  36. From storm to suppression in sepsis: are bands the link?*.
    Kangelaris KN, Seeley EJ| | PubMed
  37. Increased susceptibility to Klebsiella pneumonia and mortality in GSNOR-deficient mice.
    Tang CH, Seeley EJ, Huang X, Wolters PJ, Liu L| | PubMed
  38. Noradrenergic neurons regulate monocyte trafficking and mortality during gram-negative peritonitis in mice.
    Seeley EJ, Barry SS, Narala S, Matthay MA, Wolters PJ| | PubMed
  39. Calcium flux and endothelial dysfunction during acute lung injury: a STIMulating target for therapy.
    Seeley EJ, Rosenberg P, Matthay MA| | PubMed
  40. Updates in the management of acute lung injury: a focus on the overlap between AKI and ARDS.
    Seeley EJ| | PubMed
  41. Inflection points in sepsis biology: from local defense to systemic organ injury.
    Seeley EJ, Matthay MA, Wolters PJ| | PubMed
  42. A multicenter mortality prediction model for patients receiving prolonged mechanical ventilation.
    Carson SS, Kahn JM, Hough CL, Seeley EJ, White DB, Douglas IS, Cox CE, Caldwell E, Bangdiwala SI, Garrett JM, Rubenfeld GD, ProVent Investigators| | PubMed
  43. Parasitic infection improves survival from septic peritonitis by enhancing mast cell responses to bacteria in mice.
    Sutherland RE, Xu X, Kim SS, Seeley EJ, Caughey GH, Wolters PJ| | PubMed
  44. Systemic mast cell degranulation increases mortality during polymicrobial septic peritonitis in mice.
    Seeley EJ, Sutherland RE, Kim SS, Wolters PJ| | PubMed
  45. Decreased respiratory system compliance on the sixth day of mechanical ventilation is a predictor of death in patients with established acute lung injury.
    Seeley EJ, McAuley DF, Eisner M, Miletin M, Zhuo H, Matthay MA, Kallet RH| | PubMed
  46. Predictors of mortality in acute lung injury during the era of lung protective ventilation.
    Seeley E, McAuley DF, Eisner M, Miletin M, Matthay MA, Kallet RH| | PubMed
  47. Diabetic ketoacidosis precipitated by Staphylococcus aureus abscess and bacteremia due to acupuncture: case report and review of the literature.
    Seeley EJ, Chambers HF| | PubMed