Michael Campbell, Ph.D. received his doctoral degree in Cancer Biology from Stanford University where he remained as a postdoctoral fellow in Oncology. Dr. Campbell was appointed Assistant Professor of Surgery at Stanford University in 1992. He joined the UCSF faculty as Assistant Professor of Surgery in 1997.
Dr. Campbell's areas of interest in research include breast neoplasms, cancer vaccines, immunotherapy, immunologic adjuvants, immunologic and biological factors, gene therapy, immunology, and breast cancer.
Education
Education
1978-82, University of Puget Sound, B.S., Biology
1978-82, University of Puget Sound, B.S., Mathematics
1983-87, Stanford University, Ph.D., Cancer Biology
Publications
MOST RECENT PUBLICATIONS FROM A TOTAL OF 77
Hormone signaling and immune programs define differential endocrine responsiveness in high-risk breast tissue.
Goldhammer N, Bont M, Warhadpande S, Choi M, Cedano J, Greenwood H, Ye J, Schwartz CJ, Alvarado M, Ewing C, Goodwin K, Mukhtar RA, Wong J, Abe SE, Chandler J, Jackson J, Olopade OI, Campbell MJ, Lam A, Park C, Vertido A, van 't Veer LJ, Hylton N, Esserman LJ, Rosenbluth JM| | PubMed
Society for Cardiovascular Magnetic Resonance 2024 Cases of SCMR case series.
Kozor R, Schmitt C, Sathanandam S, Merlocco A, Murtaza S, Haque S, Bowers AL, Campbell MJ, Agarwal R, Srivastava M, Pavlov B, Lapp H, Abderrahmane M, Abdellah C, Melas G, Cardoso I, McGrath L, Cemil I, Desai T, Barhate G, Tavri O, Andres KN, Chan F, Clark DE, Lee L, Balfour P, Scothorn B, Nguyen C, Chudgar P, Burkule N, Lakshmivenkateshiah S, Crapanzano OA, Weingarten AJ, Soslow JH, Klusewitz S, Chen M, Kellman P, Hulten E, Bricha OY, Sachs V, Sayad D, Faluk M, Parra D, Surana G, Susar A, Borikar N, Romberg EK, Permut LC, Otto RK, Pillai P, Harrington K, Alsaid A, Gulhane A, Krieger E, Ordovas K, Baritussio A, Bhagirath P, Chen SSM, Dendy JM, Ganigara M, Tunks RD, Johnson JN| | PubMed
Practice Patterns in Pediatric Cardiothoracic Presurgical Conferences: A Multicenter Survey Study.
Reed B, Puranik P, Rodenbarger A, Trivedi M, Adebo DA, Beasley G, Bezold L, Campbell MJ, Carr MR, Daily J, DeBrunner M, Del Grippo E, Fifer CG, Hoffman TM, Hupp SR, Kurtz JD, Morchi G, Owada C, Peterson R, Puchalski MD, Romans RA, Saidi A, Shenoy RU, Singh AK, Tunks RD, Yohannan TM, Wilhelm CM, Patel JK| | PubMed
Pilot Study: Investigating the Local Breast Microbiome in Implant-based Breast Reconstruction Using 16S rRNA Sequencing.
Barnes LL, Parmeshwar N, Campbell M, Esserman L, Piper M| | PubMed
Immune Subtyping Identifies Patients With Hormone Receptor-Positive Early-Stage Breast Cancer Who Respond to Neoadjuvant Immunotherapy (IO): Results From Five IO Arms of the I-SPY2 Trial.
Wolf DM, Yau C, Campbell M, Glas A, Barcaru A, Mittempergher L, Kuilman M, Brown-Swigart L, Hirst G, Basu A, Magbanua M, Sayaman R, Huppert L, Delson A, I-SPY2 Investigators, Symmans WF, Borowsky A, Pohlmann P, Rugo H, Clark A, Yee D, DeMichele A, Perlmutter J, Petricoin EF, Chien J, Stringer-Reasor E, Shatsky R, Liu M, Han H, Soliman H, Isaacs C, Nanda R, Hylton N, Pusztai L, Esserman L, van 't Veer L| | PubMed
Cardiac magnetic resonance imaging in the assessment of cardiac injury and toxicity from cancer-related chemotherapy.
Johnson JN, Berthod TL, Cai X, Campbell MJ, Dodeja AK, Goode CG, Hor KN, Jacobs HM, Lee S, Loke YH, Lorenzoni RP, Morin CE, Popescu AR, Soslow JH, Trask ER, Toro-Salazar OH| | PubMed
Characterizing the recurrence of atrial arrhythmia following macro-reentrant atrial tachycardia ablation in adult patients with repaired tetralogy of Fallot.
Intratumoral Injection of mRNA-2752 and Pembrolizumab for High-Risk Ductal Carcinoma In Situ: A Phase 1 Nonrandomized Clinical Trial.
Ramalingam K, Woody R, Glencer A, Schwartz CJ, Mori H, Wong J, Hirst G, Rosenbluth J, Onishi N, Gibbs J, Hylton N, Borowsky AD, Campbell M, Esserman LJ| | PubMed
Six-Month Outcomes in the Long-Term Outcomes After the Multisystem Inflammatory Syndrome in Children Study.
Truong DT, Trachtenberg FL, Hu C, Pearson GD, Friedman K, Sabati AA, Dionne A, Oster ME, Anderson BR, Block J, Bradford TT, Campbell MJ, D'Addese L, Dummer KB, Elias MD, Forsha D, Garuba OD, Hasbani K, Hayes K, Hebson C, Jone PN, Krishnan A, Lang S, McCrindle BW, McHugh KE, Mitchell EC, Morrison T, Muniz JC, Payne RM, Portman MA, Russell MW, Sanil Y, Shakti D, Sharma K, Shea JR, Sykes M, Shekerdemian LS, Szmuszkovicz J, Thacker D, Newburger JW, MUSIC Study Investigators| | PubMed
Boys With Duchenne Muscular Dystrophy Have Diastolic Dysfunction Based on CMR.
Pexidartinib and standard neoadjuvant therapy in the adaptively randomized I-SPY2 trial for early breast cancer.
Rugo HS, Campbell M, Yau C, Jo Chien A, Wallace AM, Isaacs C, Boughey JC, Han HS, Buxton M, Clennell JL, Asare SM, Steeg K, Wilson A, Singhrao R, Matthews JB, Perlmutter J, Fraser Symmans W, Hylton NM, DeMichele AM, Yee D, Van't Veer LJ, Berry DA, Esserman LJ| | PubMed
Multi-platform biomarkers of response to an immune checkpoint inhibitor in the neoadjuvant I-SPY 2 trial for early-stage breast cancer.
Campbell MJ, Wolf DM, Yau C, Brown-Swigart L, Wulfkuhle J, Gallagher IR, Zhu Z, Bolen J, Vandenberg S, Hoyt C, Mori H, Borowsky A, Sit L, Perlmutter J, Asare SM, I-SPY2 Investigators, Nanda R, Liu MC, Yee D, DeMichele AM, Hylton NM, Pusztai L, Berry DA, Hirst GL, Petricoin EF, Veer LV, Esserman L| | PubMed
Gut and oral microbial compositional differences in women with breast cancer, women with ductal carcinoma in situ, and healthy women.
McCune E, Sharma A, Johnson B, O'Meara T, Theiner S, Campos M, Heditsian D, Brain S, Gilbert JA, Esserman L, Campbell MJ| | PubMed
Practice patterns of cardiovascular magnetic resonance use in the diagnosis of pediatric myocarditis: A survey-based study.
Jacobs HM, Soslow JH, Cornicelli MD, Merves SA, Garg R, Patel MD, Agarwal A, Misra N, DiLorenzo MP, Campbell MJ, Steele J, Co-Vu J, Robinson JD, Lee S, Johnson JN| | PubMed
Cardiac manifestations and outcomes of COVID-19 vaccine-associated myocarditis in the young in the USA: longitudinal results from the Myocarditis After COVID Vaccination (MACiV) multicenter study.
Jain SS, Anderson SA, Steele JM, Wilson HC, Muniz JC, Soslow JH, Beroukhim RS, Maksymiuk V, Jacquemyn X, Frosch OH, Fonseca B, Harahsheh AS, Buddhe S, Ashwath RC, Thacker D, Maskatia SA, Misra N, Su JA, Siddiqui S, Vaiyani D, Vaikom-House AK, Campbell MJ, Klein J, Huang S, Mathis C, Cornicelli MD, Sharma M, Nagaraju L, Ang JY, Uppu SC, Ramachandran P, Patel JK, Han F, Mandell JG, Akam-Venkata J, DiLorenzo MP, Brumund M, Bhatla P, Eshtehardi P, Mehta K, Glover K, Dove ML, Aldawsari KA, Kumar A, Barfuss SB, Dorfman AL, Minocha PK, Yonts AB, Schauer J, Cheng AL, Robinson JD, Powell Z, Srivastava S, Chelliah A, Sanil Y, Hernandez LE, Gaur L, Antonchak M, Johnston M, Reich JD, Nair N, Drugge ED, Grosse-Wortmann L| | PubMed
Society for Cardiovascular Magnetic Resonance 2023 Cases of SCMR case series.
Johnson JN, Hoke C, Chamis AL, Campbell MJ, Gearhart A, de Ferranti SD, Beroukhim R, Mozumdar N, Cartoski M, Nees S, Hudson J, Kakhi S, Daryani Y, Pasan Botheju WS, Shah KB, Makkiya M, Dimza M, Moguillansky D, Al-Ani M, Andreae A, Kim H, Ahamed H, Kannan R, Joji CA, Baritussio A, Dendy JM, Bhagirath P, Ganigara M, Hulten E, Tunks R, Kozor R, Chen SSM| | PubMed
Magnetic resonance imaging insights from active surveillance of women with ductal carcinoma in situ.
Greenwood HI, Maldonado Rodas CK, Freimanis RI, Glencer AC, Miller PN, Mukhtar RA, Brabham C, Yau C, Rosenbluth JM, Hirst GL, Campbell MJ, Borowsky A, Hylton N, Esserman LJ, Basu A| | PubMed
Lysophosphatidic Acid Receptor 1 (LPA1) Antagonists as Potential Migrastatics for Triple Negative Breast Cancer.
Liu W, Mousa AAK, Hopkins AM, Wu YF, Thu KL, Campbell M, Lees SJ, Ramachandran R, Hou J| | PubMed
Tumor microenvironmental determinants of high-risk DCIS progression.
Borowsky A, Glencer A, Ramalingam K, Schindler N, Mori H, Ghule P, Lee K, Nachmanson D, Officer A, Harismendy O, Stein J, Stein G, Evans M, Weaver D, Yau C, Hirst G, Campbell M, Esserman L| | PubMed
Days alive and out of hospital for children born with single-ventricle heart disease.
Medina CK, Prabhu NK, Alderete IS, Parker LE, Lim HK, Moya-Mendez ME, Kang L, Campbell MJ, Overbey DM, Turek JW, Andersen ND| | PubMed
Cardiac Involvement in Patients With Multisystem Inflammatory Syndrome in Adults.
La Vecchia G, Del Buono MG, Bonaventura A, Vecchiè A, Moroni F, Cartella I, Saponara G, Campbell MJ, Dagna L, Ammirati E, Sanna T, Abbate A| | PubMed
Protein signaling and drug target activation signatures to guide therapy prioritization: Therapeutic resistance and sensitivity in the I-SPY 2 Trial.
Race, Gene Expression Signatures, and Clinical Outcomes of Patients With High-Risk Early Breast Cancer.
Kyalwazi B, Yau C, Campbell MJ, Yoshimatsu TF, Chien AJ, Wallace AM, Forero-Torres A, Pusztai L, Ellis ED, Albain KS, Blaes AH, Haley BB, Boughey JC, Elias AD, Clark AS, Isaacs CJ, Nanda R, Han HS, Yung RL, Tripathy D, Edmiston KK, Viscusi RK, Northfelt DW, Khan QJ, Asare SM, Wilson A, Hirst GL, Lu R, Symmans WF, Yee D, DeMichele AM, van 't Veer LJ, Esserman LJ, Olopade OI| | PubMed
B-cells and regulatory T-cells in the microenvironment of HER2+ breast cancer are associated with decreased survival: a real-world analysis of women with HER2+ metastatic breast cancer.
Steenbruggen TG, Wolf DM, Campbell MJ, Sanders J, Cornelissen S, Thijssen B, Salgado RA, Yau C, O-Grady N, Basu A, Bhaskaran R, Mittempergher L, Hirst GL, Coppe JP, Kok M, Sonke GS, van 't Veer LJ, Horlings HM| | PubMed
Adrenal Neoplasms: Lessons from Adrenal Multidisciplinary Tumor Boards.
Chung R, Garratt J, Remer EM, Navin P, Blake MA, Taffel MT, Hackett CE, Sharbidre KG, Tu W, Low G, Bara M, Carney BW, Corwin MT, Campbell MJ, Lee JT, Lee CY, Dueber JC, Shehata MA, Caoili EM, Schieda N, Elsayes KM| | PubMed
Lexicon for adrenal terms at CT and MRI: a consensus of the Society of Abdominal Radiology adrenal neoplasm disease-focused panel.
Glazer DI, Mayo-Smith WW, Remer EM, Caoili EM, Song JH, Taffel MT, Lee JT, Brook OR, Shinagare AB, Blake MA, Elsayes KM, Schieda N, Westphalen AC, Campbell MJ, Corwin MT| | PubMed
Identifying Good Candidates for Active Surveillance of Ductal Carcinoma In Situ: Insights from a Large Neoadjuvant Endocrine Therapy Cohort.
Glencer AC, Miller PN, Greenwood H, Maldonado Rodas CK, Freimanis R, Basu A, Mukhtar RA, Brabham C, Kim P, Hwang ES, Rosenbluth JM, Hirst GL, Campbell MJ, Borowsky AD, Esserman LJ| | PubMed
Limited disease progression in endocrine surgery patients with treatment delays due to COVID-19.
Collins RA, DiGennaro C, Beninato T, Gartland RM, Chaves N, Broekhuis JM, Reddy L, Lee J, Deimiller A, Alterio MM, Campbell MJ, Lee YJ, Khilnani TK, Stewart LA, O'Brien MA, Alvarado MVY, Zheng F, McAneny D, Liou R, McManus C, Dream SY, Wang TS, Yen TW, Alhefdhi A, Finnerty BM, Fahey TJ, Graves CE, Laird AM, Nehs MA, Drake FT, Lee JA, McHenry CR, James BC, Pasieka JL, Kuo JH, Lubitz CC| | PubMed
Modulation of the immune microenvironment of high-risk ductal carcinoma in situ by intralesional pembrolizumab injection.
Glencer AC, Wong JM, Hylton NM, Krings G, McCune E, Rothschild HT, Loveday TA, Alvarado MD, Esserman LJ, Campbell MJ| | PubMed
Characterizing the Tumor Immune Microenvironment with Tyramide-Based Multiplex Immunofluorescence.
Germline genetic contribution to the immune landscape of cancer.
Sayaman RW, Saad M, Thorsson V, Hu D, Hendrickx W, Roelands J, Porta-Pardo E, Mokrab Y, Farshidfar F, Kirchhoff T, Sweis RF, Bathe OF, Heimann C, Campbell MJ, Stretch C, Huntsman S, Graff RE, Syed N, Radvanyi L, Shelley S, Wolf D, Marincola FM, Ceccarelli M, Galon J, Ziv E, Bedognetti D| | PubMed
Adrenal Tumors Found During Staging and Surveillance for Colorectal Cancer: Benign Incidentalomas or Metastatic Disease?
Yanagisawa M, Malik DG, Loehfelm TW, Fananapazir G, Corwin MT, Campbell MJ| | PubMed
Co-expression modules identified from published immune signatures reveal five distinct immune subtypes in breast cancer.
Amara D, Wolf DM, van 't Veer L, Esserman L, Campbell M, Yau C| | PubMed
Characterizing the immune microenvironment in high-risk ductal carcinoma in situ of the breast.
Campbell MJ, Baehner F, O'Meara T, Ojukwu E, Han B, Mukhtar R, Tandon V, Endicott M, Zhu Z, Wong J, Krings G, Au A, Gray JW, Esserman L| | PubMed
The prognostic implications of macrophages expressing proliferating cell nuclear antigen in breast cancer depend on immune context.
Campbell MJ, Wolf D, Mukhtar RA, Tandon V, Yau C, Au A, Baehner F, van't Veer L, Berry D, Esserman LJ| | PubMed
Biology of breast cancer in Nigerian women: a pilot study.
Adisa CA, Eleweke N, Alfred AA, Campbell MJ, Sharma R, Nseyo O, Tandon V, Mukhtar R, Greninger A, Risi JD, Esserman LJ| | PubMed
Elevated levels of proliferating and recently migrated tumor-associated macrophages confer increased aggressiveness and worse outcomes in breast cancer.
Mukhtar RA, Moore AP, Tandon VJ, Nseyo O, Twomey P, Adisa CA, Eleweke N, Au A, Baehner FL, Moore DH, McGrath MS, Olopade OI, Gray JW, Campbell MJ, Esserman LJ| | PubMed
Elevated PCNA+ tumor-associated macrophages in breast cancer are associated with early recurrence and non-Caucasian ethnicity.
Mukhtar RA, Moore AP, Nseyo O, Baehner FL, Au A, Moore DH, Twomey P, Campbell MJ, Esserman LJ| | PubMed
Tumor-associated macrophages in breast cancer as potential biomarkers for new treatments and diagnostics.
Mukhtar RA, Nseyo O, Campbell MJ, Esserman LJ| | PubMed
Proliferating macrophages associated with high grade, hormone receptor negative breast cancer and poor clinical outcome.
Campbell MJ, Tonlaar NY, Garwood ER, Huo D, Moore DH, Khramtsov AI, Au A, Baehner F, Chen Y, Malaka DO, Lin A, Adeyanju OO, Li S, Gong C, McGrath M, Olopade OI, Esserman LJ| | PubMed
Fluvastatin reduces proliferation and increases apoptosis in women with high grade breast cancer.
Garwood ER, Kumar AS, Baehner FL, Moore DH, Au A, Hylton N, Flowers CI, Garber J, Lesnikoski BA, Hwang ES, Olopade O, Port ER, Campbell M, Esserman LJ| | PubMed
Nordihydroguaiaretic acid (NDGA), an inhibitor of the HER2 and IGF-1 receptor tyrosine kinases, blocks the growth of HER2-overexpressing human breast cancer cells.
Campbell MJ, Esserman LJ, Zhou Y, Shoemaker M, Lobo M, Borman E, Baehner F, Kumar AS, Adduci K, Marx C, Petricoin EF, Liotta LA, Winters M, Benz S, Benz CC| | PubMed
Challenge with mammary tumor cells expressing MHC class II and CD80 prevents the development of spontaneously arising tumors in MMTV-neu transgenic mice.
Jabrane-Ferrat N, Campbell MJ, Esserman LJ, Peterlin BM| | PubMed
A call for clinical trials: lipophilic statins may prove effective in treatment and prevention of particular breast cancer subtypes.
Kumar AS, Campbell M, Benz CC, Esserman LJ| | PubMed
Diarylureas are small-molecule inhibitors of insulin-like growth factor I receptor signaling and breast cancer cell growth.
Combined syngeneic bone marrow transplantation and immunotherapy of a murine B-cell lymphoma: active immunization with tumor-derived idiotypic immunoglobulin.
Kwak LW, Campbell MJ, Zelenetz AD, Levy R| | PubMed
Idiotype vaccination against murine B cell lymphoma. Humoral and cellular requirements for the full expression of antitumor immunity.
Idiotypic variation in a human B lymphoma cell line.
Berinstein N, Campbell MJ, Lam K, Carswell C, Levy S, Levy R| | PubMed
Functional immunoglobulin light chain genes are replaced by ongoing rearrangements of germline V kappa genes to downstream J kappa segment in a murine B cell line.
Idiotype vaccination against murine B cell lymphoma. Humoral and cellular responses elicited by tumor-derived immunoglobulin M and its molecular subunits.
Campbell MJ, Carroll W, Kon S, Thielemans K, Rothbard JB, Levy S, Levy R| | PubMed
Studies on B lymphoid tumors treated with monoclonal anti-idiotype antibodies: correlation with clinical responses.
Lowder JN, Meeker TC, Campbell M, Garcia CF, Gralow J, Miller RA, Warnke R, Levy R| | PubMed
Influence of avidity and idiotope recognition on the modulation of surface immunoglobulin on malignant human B cells by rat monoclonal anti-idiotype antibodies.
PubMed