University of California San Francisco

Norah Terrault - 144
Norah
Terrault
MD, MPH

Professor of Clinical Medicine & Surgery
Departments of Medicine & Surgery
Director of Viral Hepatitis Research in Liver Transplantation

Address

513 Parnassus Avenue, MSB, #357
San Francisco, CA 94143
United States

Email: [email protected]
Phone: 415-476-2227
Fax: 415-476-0659

    Biography

    Dr. Norah Terrault is a hepatologist or liver specialist who is recognized internationally for the treatment of viral hepatitis and liver transplantation. Her research includes the study of viral hepatitis and its progression and treatment, especially in liver transplant patients. Her research includes several clinical trials related to preventing and treating chronic hepatitis C and B. Her studies in this area have been presented to the American Association for the Study of Liver Diseases, the leading organization for research in liver disease.

    Terrault completed medical training at the University of Alberta and specialty medical training in Internal Medicine and Gastroenterology at the University of Toronto, both in Canada. Her post-doctoral fellowship in hepatology and viral hepatitis was completed at the University of California, San Francisco while earning a concurrent master's degree in public health from the University of California at Berkeley. She joined the medical staff at UCSF Medical Center in 1997.

    Education

    Institution Degree Dept or School End Date
    University of California, San Francisco Post-Doc Fellow/Scholar Medicine 1995
    University of Alberta M.D. School of Medicine 1987
    University of California, San Francisco Residency
    University of California, San Francisco Clinical Fellowship Gastroenterology

    Board Certifications

    American Board of Internal Medicine, Internal Medicine

    American Board of Internal Medicine, Gastroenterology

    Clinical Expertise

    Alcoholic Liver Disease
    Autoimmune Hepatitis
    Benign Liver Tumors
    Cirrhosis
    Fulminant Hepatic Failure
    Hepatitis B
    Hepatitis C
    Hepatocellular Carcinoma (Liver Cancer)
    Live Donor Liver Transplantation
    Liver Transplantation
    Nonalcoholic Fatty Liver Disease
    Pancreas Transplantation
    Primary Biliary Cirrhosis
    Primary Sclerosing Cholangitis

    Clinical Trials

    1. Related Conditions: Hepatitis C, Viruses, Hepatocellular Cancer, Liver Cancer, Hepatitis, Cirrhosis, Liver Transplant, Hepatitis A| Start Date: | End Date:
    2. Related Conditions: Hepatitis B, Liver Disease, Liver Transplant, Hepatitis A, Hepatitis| Start Date: | End Date:

    Program Affiliations

    UCSF Liver Center

    In the News

    December, 20, 2014 | UCSF Transplant Surgery

    Grants and Funding

    • USC Cirrhosis Clinical Center | NIH | 2021-09-22 - 2026-08-31 | Role: Principal Investigator
    • Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) | NIH | 2002-06-15 - 2024-06-30 | Role: Principal Investigator
    • Hepatitis B Research Network (HBRN): Natural History and Treatment Studies | NIH | 2008-09-30 - 2021-05-31 | Role: Principal Investigator
    • Bay Area Hepatitis C Cooperative Research Center | NIH | 2010-06-15 - 2016-05-31 | Role: Co-Investigator
    • General Clinical Research Center | NIH | 1974-12-01 - 2009-03-31 | Role: Co-Investigator
    • Resistance to Antiviral Therapy in Chronic Hepatitis C | NIH | 2001-08-01 - 2007-04-30 | Role: Principal Investigator

    Research Narrative

    My research focuses on the natural history and treatment of hepatitis C virus (HCV) and hepatitis B virus (HBV), particularly in special populations, including those undergoing liver transplantation. Work in progress addresses the natural history of post-transplant disease and specific therapies to prevent infection or modify HCV and HBV disease progression and loss of grafts from recurrent disease.

    Our virological analyses are focused on characterization of viral mutations that occur in liver transplant recipients receiving antiviral therapies and assessment of the effect of these variant viruses on the natural history and severity of disease post-transplantation. Knowledge of these factors may allow improved organ allocation by identifying subsets of patients with HCV recurrence in liver grafts who would be favorable or unfavorable candidates for retransplantation. 

    Research Interests

    Liver Injury and Repair

    Hepatitis B virus (HBV)

    Hepatitis C virus (HCV)

    Publications

    MOST RECENT PUBLICATIONS FROM A TOTAL OF 414
    1. Longer Travel and Traffic are Associated with Adult Liver Transplant Waitlist Mortality in the United States.
      Zhou K, Albertian R, Wong C, Kuo LS, Thompson LK, Dodge JL, Mehta N, Terrault NA, Cockburn MG| | PubMed
    2. Global burden of HBV-related liver disease: Primary liver cancer due to chronic HBV infection increased in over one-third of countries globally from 2000 to 2021.
      Danpanichkul P, Duangsonk K, Chen VL, Saokhieo P, Dejvajara D, Sukphutanan B, Aboona MB, Lopimpisuth C, Pang Y, Ibrahim AF, Fallon MB, Huang DQ, Kim D, Singal AG, Yang JD, Aqel BA, Terrault NA, Wijarnpreecha K| | PubMed
    3. Quest for HBV functional cure: what have we learnt from silencing RNAs?
      Terrault N, Lok AS| | PubMed
    4. Number of people treated for hepatitis C virus infection in 2014-2023 and applicable lessons for new HBV and HDV therapies.
      Razavi HA, Waked I, Qureshi H, Kondili LA, Duberg AS, Aleman S, Tanaka J, Lazarus JV, Low-Beer D, Abbas Z, Rached AA, Aghemo A, Aho I, Akarca US, Al-Busafi SA, Al-Hamoudi WK, Al-Naamani K, Alaama AS, Aldar MM, Alghamdi M, Gonzalez MA, Alserehi H, Anand AC, Asselah T, Assiri AM, Athanasakis K, Atugonza R, Ben-Ari Z, Berg T, Brandão-Mello CE, Brown ASM, Brown KA, Brown RS, Bruggmann P, Brunetto MR, Buti M, Cheinquer H, Christensen PB, Chulanov V, Cisneros Garza LE, Coffin CS, Coppola N, Craxi A, Crespo J, Cui F, Dalgard O, De La Torre A, De Ledinghen V, Dieterich D, Drazilova S, Dufour JF, El-Kassas M, Elbadri M, Esmat G, Mur RE, Eurich B, Faini D, Ferreira PRA, Flisiak R, Frankova S, Gaeta GB, Gamkrelidze I, Gane EJ, Garcia V, García-Samaniego J, Gemilyan M, Gottfredsson M, Gschwantler M, Gurski APM, Hajarizadeh B, Hamid SS, Hatzakis A, Hercun J, Hockicková I, Huang JF, Hunyady B, Hutchinson SJ, Ishikawa N, Izumi K, Izzi A, Janicko M, Jarcuska P, Jeruma A, Johannessen A, Kaliaskarova KS, Kao JH, Kielland KB, Kodjoh N, Kottilil S, Kristian P, Kwo PY, Lagging M, Lam H, Lázaro P, Lee MH, Lens S, Liakina V, Lim YS, Makara M, Manns M, Manzengo CM, Memon S, Mendes-Correa MC, Messina V, Midgard H, Murphy N, Musabaev E, Naveira MCM, Nde H, Negro F, Nim N, Ocama P, Olafsson S, Omuemu CE, Pamplona JJ, Pan CQ, Papatheodoridis GV, Pimenov N, Poustchi H, Quaranta MG, Ramji A, Rautiainen H, Razavi-Shearer DM, Razavi-Shearer K, Ridruejo E, Ríos-Hincapié CY, Sadirova S, Sanai FM, Sarrazin C, Sarybayeva G, Schréter I, Seguin-Devaux C, Sereno LS, Shiha G, Smith J, Soliman R, Sonderup MW, Spearman CW, Stauber RE, Stedman CAM, Sypsa V, Tacke F, Terrault NA, Tolmane I, Van Welzen B, Voeller AS, Waheed Y, Wallace C, Whittaker RN, W-S Wong V, Ydreborg M, Yesmembetov K, Yu ML, Zeuzem S, Zuckerman E| | PubMed
    5. Association of Alcohol and Incremental Cardiometabolic Risk Factors With Liver Disease: A National Cross-sectional Study.
      Lee BP, Molina J, Kim S, Dodge JL, Terrault NA| | PubMed
    6. Antivirals in Preventing Perinatal Transmission of Hepatitis B: Start and Stop Times are Shifting.
      Terrault NA, Vargas HE| | PubMed
    7. Epidemiology and Outcomes of Alcohol-Associated Hepatitis in Adolescents and Young Adults.
      Flemming JA, Djerboua M, Chapman O, Ayonrinde O, Terrault NA| | PubMed
    8. Metabolic dysfunction and alcohol-related liver disease (MetALD): Position statement by an expert panel on alcohol-related liver disease.
      Arab JP, Díaz LA, Rehm J, Im G, Arrese M, Kamath PS, Lucey MR, Mellinger J, Thiele M, Thursz M, Bataller R, Burton R, Chokshi S, Francque SM, Krag A, Lackner C, Lee BP, Liangpunsakul S, MacClain C, Mandrekar P, Mitchell MC, Morgan MY, Morgan TR, Pose E, Shah VH, Shawcross D, Sheron N, Singal AK, Stefanescu H, Terrault N, Trépo E, Moreno C, Louvet A, Mathurin P| | PubMed
    9. Trends in Alcohol Use After the COVID-19 Pandemic: A National Cross-Sectional Study.
      Ayyala-Somayajula D, Dodge JL, Leventhal AM, Terrault NA, Lee BP| | PubMed
    10. HBV RNA as a Biomarker for Safe Antiviral Discontinuation: A Prospective Study of Nucleos(t)ide Analogue Withdrawal.
      Terrault NA, Sterling R, Lok AS, Ghany MG, Feld JJ, Cloherty G, Wahed AS, Yang X| | PubMed