Biography
Jhoanne (Joey) Bautista MD PhD is a General Surgery Resident in the UCSF Department of Surgery. During her research years, Dr. Bautista was a Research Fellow in the UCSF Diabetes Center where she applied bioinformatics to the study of the development of tolerogenic antigen presenting cells in both the thymus and periphery.
Education
Barnard College (New York, NY) - BA Biochemistry 1999
Massachusetts Institute of Technology (Cambridge, MA) - MS Inorganic Chemistry 2003
Washington University in St. Louis School of Medicine (St. Louis, MO) - PhD Immunology 2014
Washington University in St. Louis School of Medicine (St. Louis, MO) - MD 2014
University of California San Francisco Medical Center - General Surgery Intern - 2014-2015
University of California San Francisco Medical Center - General Surgery Resident - 2015-present
Resident Research Fellow - Diabetes Center - 2017-2019
Postdoctoral Trainee/Fellow - Diabetes Center - 2017-Present
Clinical Interests
Abdominal Transplantation
Surgical Management of Autoimmune Diseases
In the News
Research Interests
Thymic development
Antigen presentation in auto/alloreactivity and tolerance
Transplant immunology
Bioinformatics
Research Pathways
Publications
- Single-cell multiomics defines tolerogenic extrathymic Aire-expressing cells with unique homology to thymic epithelium.| | UCSF Research Profile
- Single-cell multiomics defines tolerogenic extrathymic Aire-expressing populations with unique homology to thymic epithelium.| | PubMed
- Single-cell transcriptional profiling of human thymic stroma uncovers novel cellular heterogeneity in the thymic medulla.| | PubMed
- Elastase 3B mutation links to familial pancreatitis with diabetes and pancreatic adenocarcinoma.| | PubMed
- Aire deficiency during early pregnancy leads to maternal T cell imbalance and embryo loss.| | UCSF Research Profile
- Autoimmune regulator gene supports maternal-fetal immune tolerance during early pregnancy.| | UCSF Research Profile
- A broad range of self-reactivity drives thymic regulatory T cell selection to limit responses to self.| | PubMed
- Responsiveness to IL-2 characterizes a stable Foxp3+ subset in mice (148.16).| | UCSF Research Profile
- Thymic and peripheral differentiation of regulatory T cells.| | PubMed
- Sliding set-points of immune responses for therapy of autoimmunity.| | PubMed
- Absence of P-selectin in recipients of allogeneic bone marrow transplantation ameliorates experimental graft-versus-host disease.| | PubMed
- P-Selectin Regulates Leukocyte Trafficking And Experimental Graft-Versus-Host-Disease After Allogeneic Bone Marrow Transplantation.| | UCSF Research Profile
- Intraclonal competition limits the fate determination of regulatory T cells in the thymus.| | PubMed
- SY-24 Thymic and peripheral regulatory T-cell development.| | UCSF Research Profile
- An ITAM-signaling pathway controls cross-presentation of particulate but not soluble antigens in dendritic cells.| | PubMed
- Neutrophil-mediated oxidative burst and host defense are controlled by a Vav-PLCgamma2 signaling axis in mice.| | PubMed