University of California San Francisco

Andrew Posselt MD
Andrew
Posselt
MD, PhD

Professor of Surgery
Division of Transplant Surgery
Director, Pancreatic Islet Transplant Program

Address

35 Medical Center Way, #001
San Francisco, CA 94143
United States

Email: [email protected]
Phone: 415-514-5606
Fax: 415-353-8709

Biography

Dr. Andrew Posselt, a bariatric and transplant surgeon, is director of the Pancreatic Islet Transplantation Program at UCSF Medical Center. He specializes in adult and pediatric kidney, liver and pancreas transplantation, laparoscopic and open (traditional) bariatric surgery, robotic surgery and performed the first robotic donor nephrectomy at UCSF in May, 2023.

In addition to caring for patients, Posselt conducts research on pancreatic islet cell transplantation, a procedure that can allow people with type 1 diabetes to discontinue insulin therapy. He also investigates mechanisms by which a transplant recipient's body rejects or tolerates tissue from a donor who isn't genetically identical, and he studies the metabolic and biochemical consequences of bariatric surgery.

Posselt earned his medical degree and a doctorate in immunology from the University of Pennsylvania. He completed residencies in internal medicine and general surgery as well as a transplant fellowship at UCSF, before joining the staff in 2003.

Posselt is a member of several professional and honorary societies, and has given presentations on transplant issues related to patient care and research. At UCSF, he supervises residents and fellows in transplant services and general surgery.

Videos

Education

Institution Degree Dept or School End Date
University of Pennsylvania PhD Immunology 1993
University of Pennsylvania M.D. School of Medicine 1993
University of California, San Francisco Residency Internal Medicine

Board Certifications

  • American Board of Internal Medicine, 1996
  • American Board of Surgery, 2002

Clinical Expertise

Bariatric Surgery (Laparoscopic and Open)
Bile Duct Injuries
Bile Duct Strictures
Choledochal Cyst Disease
End-Stage Kidney Disease
Fulminant Hepatic Failure
Hepatitis B
Hepatitis C
Hepatocellular Carcinoma (Primary Liver Cancer)
Kidney Transplantation
Laparoscopic Donor Nephrectomy
Liver Cysts
Liver Transplantation
Nonalcoholic Fatty Liver Disease
Pancreas Transplantation
Pediatric Liver Transplantation
Pediatric Kidney Transplantation
Portal Hypertension
Islet Cell Transplantation
Autologous Islet Cell Transplantation

Clinical Trials

  1. Treatment of Type I Diabetes by Islet Transplantation Into the Gastric Submucosa Study Protocol (NCT02402439)
    Related Conditions: Diabetes, Diabetes Type 1| Start Date: | End Date:
  2. Extended Follow-Up After Islet Transplantation in T1D (NCT01369082)
    Related Conditions: Diabetes, Diabetes Type 1, Islet Transplantation| Start Date: | End Date:
  3. Pancreatic Islet Transplantation Into the Gastric Submucosa (NCT01571817)
    Related Conditions: Diabetes, Diabetes Type 1| Start Date: | End Date:
  4. Islet Transplantation in Type 1 Diabetes (NCT00434811)
    Related Conditions: Diabetes, Diabetes Type 1| Start Date: | End Date:
  5. Peritransplant Deoxyspergualin in Islet Transplantation in Type 1 Diabetes (NCT00434850)
    Related Conditions: Diabetes, Diabetes Type 1| Start Date: | End Date:

Program Affiliations

Pancreatic Islet Transplantation Program

Bariatric Surgery Center

ABO-Incompatible Kidney Transplant Program

Grants and Funding

  • Vertical Sleeve Gastrectomy for Treatment of NASH: a pilot randomized control | NIH | 2021-07-14 - 2024-05-31 | Role: Co-Principal Investigator
  • Treatment of Type I Diabetes by Islet Transplantation into the Gastric Submucosa | NIH | 2014-05-01 - 2021-04-30 | Role: Principal Investigator
  • "Advancing Islet Transplant for Type 1 Diabetes Care" | NIH | 2009-09-30 - 2013-07-31 | Role: Principal Investigator
  • Effect of Obesity on Long-Term Clinical Outcomes after Kidney Donation | NIH | 2009-09-21 - 2012-06-30 | Role: Principal Investigator

Research Interests

  • Transplantation of pancreatic islets as treatment for type 1 diabetes mellitus
  • Assessment of long-term clinical outcomes in kidney donors
  • Metabolic and biochemical consequences of bariatric surgery
  • Clinical outcomes of bariatric surgery in patients with end-stage kidney or liver disease

Publications

MOST RECENT PUBLICATIONS FROM A TOTAL OF 118
  1. Preoperative ERCP has no impact on islet yield following total pancreatectomy and islet autotransplantation (TPIAT): Results from the Prospective Observational Study of TPIAT (POST) cohort.
    Trikudanathan G, Elmunzer BJ, Yang Y, Abu-El-Haija M, Adams D, Ahmad S, Balamurugan AN, Beilman GJ, Chinnakotla S, Conwell DL, Freeman ML, Gardner TB, Hatipoglu B, Hodges JS, Kirchner V, Lara LF, Long-Simpson L, Mitchell R, Morgan K, Nathan JD, Naziruddin B, Posselt A, Pruett TL, Schwarzenberg SJ, Singh VK, Smith K, Wijkstrom M, Witkowski P, Bellin MD| | PubMed
  2. COVID-19 and Abdominal Transplant: A Stepwise Approach to Practice During Pandemic Conditions.
    Syed SM, Gardner J, Roll G, Webber A, Mehta N, Shoji J, Adelmann D, Niemann C, Braun HJ, Mello A, Yao F, Posselt A, Kang SM, Hirose R, Roberts J, Feng S, Ascher N, Stock P, Freise C| | PubMed
  3. Phase 3 trial of human islet-after-kidney transplantation in type 1 diabetes.
    Markmann JF, Rickels MR, Eggerman TL, Bridges ND, Lafontant DE, Qidwai J, Foster E, Clarke WR, Kamoun M, Alejandro R, Bellin MD, Chaloner K, Czarniecki CW, Goldstein JS, Hering BJ, Hunsicker LG, Kaufman DB, Korsgren O, Larsen CP, Luo X, Naji A, Oberholzer J, Posselt AM, Ricordi C, Senior PA, Shapiro AMJ, Stock PG, Turgeon NA| | PubMed
  4. Ampullary stenosis and choledocholithiasis post Roux-En-Y gastric bypass: challenges of biliary access and intervention.
    Wisneski AD, Carter J, Nakakura EK, Posselt A, Rogers SJ, Cello JP, Arain M, Kirkwood KS, Hirose K, Stewart L, Corvera CU| | PubMed
  5. Long-term follow-up of beta cell replacement therapy in 10 HIV-infected patients with renal failure secondary to type 1 diabetes mellitus.
    Roll GR, Posselt AM, Freise J, Baird J, Syed S, Mo Kang S, Hirose R, Szot GL, Zarinsefat A, Feng S, Worner G, Sarwal M, Stock PG| | PubMed
  6. Obesity, transplantation, and bariatric surgery: An evolving solution for a growing epidemic.
    Diwan TS, Lee TC, Nagai S, Benedetti E, Posselt A, Bumgardner G, Noria S, Whitson BA, Ratner L, Mason D, Friedman J, Woodside KJ, Heimbach J| | PubMed
  7. Increases in PYY and uncoupling of bone turnover are associated with loss of bone mass after gastric bypass surgery.
    Kim TY, Shoback DM, Black DM, Rogers SJ, Stewart L, Carter JT, Posselt AM, King NJ, Schafer AL| | PubMed
  8. A Study on the Effect of Patient Characteristics, Geographical Utilization, and Patient Outcomes for Total Pancreatectomy Alone and Total Pancreatectomy With Islet Autotransplantation in Patients With Pancreatitis in the United States.
    Lara LF, Bellin MD, Ugbarugba E, Nathan JD, Witkowski P, Wijkstrom M, Steel JL, Smith KD, Singh VK, Schwarzenberg SJ, Pruett TL, Naziruddin B, Long-Simpson L, Kirchner VA, Gardner TB, Freeman ML, Dunn TB, Chinnakotla S, Beilman GJ, Adams DB, Morgan KA, Abu-El-Haija MA, Ahmad S, Posselt AM, Hughes MG, Conwell DL| | PubMed
  9. Outcomes of Sleeve Gastrectomy in Obese Liver Transplant Candidates.
    Sharpton SR, Terrault NA, Posselt AM| | PubMed
  10. Changes in Lean Mass, Absolute and Relative Muscle Strength, and Physical Performance After Gastric Bypass Surgery.
    Alba DL, Wu L, Cawthon PM, Mulligan K, Lang T, Patel S, King NJ, Carter JT, Rogers SJ, Posselt AM, Stewart L, Shoback DM, Schafer AL| | PubMed
118
View all 118 Publications
MOST RECENT PUBLICATIONS FROM A TOTAL OF 118
  1. Association between bariatric surgery after kidney transplantation and graft and survival outcomes.
    Ku E, McCulloch CE, Roll GR, Adey D, Sood P, Posselt A, Grimes BA, Johansen KL| | PubMed
  2. Islet Isolation Outcomes in Patients Undergoing Total Pancreatectomy With Islet Autotransplantation in the POST Consortium.
    Mattke J, Eaton A, Wijkstrom M, Witkowski P, Trikudanathan G, Singh VK, Schwarzenberg SJ, Ramanathan K, Pruett TL, Posselt A, Nathan JD, Morgan K, Mokshagundam SP, Lara L, Gardner TB, Freeman M, Downs E, Chinnakotla S, Beilman GJ, Ahmad S, Adams D, Abu-El-Haija M, Naziruddin B, Bellin MD| | PubMed
  3. Skeletal effects of sleeve gastrectomy, by sex and menopausal status and compared to Roux-en-Y gastric bypass surgery.
    Wu KC, Wu PH, Kazakia G, Patel S, Black DM, Lang TF, Kim TY, King NJ, Hoffmann TJ, Chang H, Linfield G, Palilla S, Rogers SJ, Carter JT, Posselt AM, Schafer AL| | PubMed
  4. Skeletal effects of sleeve gastrectomy, by sex and menopausal status and in comparison to Roux-en-Y gastric bypass surgery.
    Wu KC, Wu PH, Kazakia G, Patel S, Black DM, Lang TF, Kim TY, King NJ, Hoffman TJ, Chang H, Linfield G, Palilla S, Rogers SJ, Carter JT, Posselt AM, Schafer AL| | PubMed
  5. Alteration in the gut microbiome is associated with changes in bone metabolism after laparoscopic sleeve gastrectomy.
    Wu KC, McCauley KE, Lynch SV, Nayak RR, King NJ, Patel S, Kim TY, Condra K, Fadrosh D, Nguyen D, Lin DL, Lynch K, Rogers SJ, Carter JT, Posselt AM, Stewart L, Schafer AL| | PubMed
  6. Nutritional Risks in Patients Undergoing Total Pancreatectomy Islet AutoTransplantation in the POST Consortium.
    Downs EM, Eaton A, Witkowski P, Wijkstrom M, Walsh M, Trikudanathan G, Singh VK, Schwarzenberg SJ, Pruett TL, Posselt A, Naziruddin B, Nathan JD, Mokshagundam SP, Morgan K, Lara LF, Gardner TB, Freeman ML, Ellery K, Chinnakotla S, Beilman GJ, Adams D, Ahmad S, Abu-El-Haija M, Bellin MD| | PubMed
  7. A Multi-Modal Approach to Islet and Pancreas Transplantation With Calcineurin-Sparing Immunosuppression Maintains Long-Term Insulin Independence in Patients With Type I Diabetes.
    Wisel SA, Posselt AM, Szot GL, Nunez M, Santos-Parker K, Gardner JM, Worner G, Roll GR, Syed S, Kelly Y, Ward C, Tavakol M, Johnson K, Masharani U, Stock PG| | PubMed
  8. Intestinal Calcium Absorption Decreases After Laparoscopic Sleeve Gastrectomy Despite Optimization of Vitamin D Status.
    Wu KC, Cao S, Weaver CM, King NJ, Patel S, Kim TY, Black DM, Kingman H, Shafer MM, Rogers SJ, Stewart L, Carter JT, Posselt AM, Schafer AL| | PubMed
  9. Characterization of human islet function in a convection-driven intravascular bioartificial pancreas.
    Santandreu AG, Taheri-Tehrani P, Feinberg B, Torres A, Blaha C, Shaheen R, Moyer J, Wright N, Szot GL, Fissell WH, Vartanian S, Posselt A, Roy S| | PubMed
  10. Prebiotic to Improve Calcium Absorption in Postmenopausal Women After Gastric Bypass: A Randomized Controlled Trial.
    Wu KC, Cao S, Weaver CM, King NJ, Patel S, Kingman H, Sellmeyer DE, McCauley K, Li D, Lynch SV, Kim TY, Black DM, Shafer MM, Özçam M, Lin DL, Rogers SJ, Stewart L, Carter JT, Posselt AM, Schafer AL| | PubMed
  11. Islets Transplantation at a Crossroads - Need for Urgent Regulatory Update in the United States: Perspective Presented During the Scientific Sessions 2021 at the American Diabetes Association Congress.
    Witkowski P, Philipson LH, Buse JB, Robertson RP, Alejandro R, Bellin MD, Kandeel F, Baidal D, Gaglia JL, Posselt AM, Anteby R, Bachul PJ, Al-Salmay Y, Jayant K, Perez-Gutierrez A, Barth RN, Fung JJ, Ricordi C| | PubMed
  12. Advantages and Limitations of Clinical Scores for Donation After Circulatory Death Liver Transplantation.
    Meier RPH, Kelly Y, Yamaguchi S, Braun HJ, Lunow-Luke T, Adelmann D, Niemann C, Maluf DG, Dietch ZC, Stock PG, Kang SM, Feng S, Posselt AM, Gardner JM, Syed SM, Hirose R, Freise CE, Ascher NL, Roberts JP, Roll GR| | PubMed
  13. Surgical approach and short-term outcomes in adults and children undergoing total pancreatectomy with islet autotransplantation: A report from the Prospective Observational Study of TPIAT.
    Nathan JD, Yang Y, Eaton A, Witkowski P, Wijkstrom M, Walsh M, Trikudanathan G, Singh VK, Schwarzenberg SJ, Pruett TL, Posselt A, Naziruddin B, Mokshagundam SP, Morgan K, Lara LF, Kirchner V, He J, Gardner TB, Freeman ML, Ellery K, Conwell DL, Chinnakotla S, Beilman GJ, Ahmad S, Abu-El-Haija M, Hodges JS, Bellin MD| | PubMed
  14. Bariatric surgery prior to transplantation and risk of early hospital re-admission, graft failure, or death following kidney transplantation.
    Ku E, McCulloch CE, Roll GR, Posselt A, Grimes BA, Johansen KL| | PubMed
  15. The Association of Smoking and Alcohol Abuse on Anxiety and Depression in Patients With Recurrent Acute or Chronic Pancreatitis Undergoing Total Pancreatectomy and Islet Autotransplantation: A Report From the Prospective Observational Study of TPIAT Cohor
    Lara LF, Wastvedt S, Hodges JS, Witkowski P, Wijkstrom M, Walsh RM, Singh VK, Schwarzenberg SJ, Pruett TL, Posselt A, Naziruddin B, Nathan JD, Morgan KA, Mitchell R, Kirchner VA, Mokshagundam SL, Hatipoglu B, Gardner TB, Freeman ML, Chinnakotla S, Beilman GJ, Abu-El-Haija M, Conwell DL, Bellin MD, POST study consortium| | PubMed
  16. Arguments against the Requirement of a Biological License Application for Human Pancreatic Islets: The Position Statement of the Islets for US Collaborative Presented during the FDA Advisory Committee Meeting.
    Witkowski P, Odorico J, Pyda J, Anteby R, Stratta RJ, Schrope BA, Hardy MA, Buse J, Leventhal JR, Cui W, Hussein S, Niederhaus S, Gaglia J, Desai CS, Wijkstrom M, Kandeel F, Bachul PJ, Becker YT, Wang LJ, Robertson RP, Olaitan OK, Kozlowski T, Abrams PL, Josephson MA, Andreoni KA, Harland RC, Kandaswamy R, Posselt AM, Szot GL, Ricordi C| | PubMed
  17. Targeting CXCR1/2 in the first multicenter, double-blinded, randomized trial in autologous islet transplant recipients.
    Witkowski P, Wijkstrom M, Bachul PJ, Morgan KA, Levy M, Onaca N, Chaidarun SS, Gardner T, Shapiro AMJ, Posselt A, Ahmad SA, Daffonchio L, Ruffini PA, Bellin MD| | PubMed
  18. Sleeve gastrectomy prior to liver transplantation is superior to medical weight loss in reducing posttransplant metabolic complications.
    Sharpton SR, Terrault NA, Tavakol MM, Posselt AM| | PubMed
  19. Anticoagulation practices in total pancreatectomy with autologous islet cell transplant patients: an international survey of clinical programs.
    Desai CS, Szempruch KR, Vonderau JS, Chetboun M, Pattou F, Coates T, De Paep DL, Hawthorne WJ, Khan KM, de Koning EJP, Naziruddin B, Posselt A, Schrope BA, Wijkstrom M, Witkowski P, Shapiro AMJ| | PubMed
  20. Circulating miRNA in Patients Undergoing Total Pancreatectomy and Islet Autotransplantation.
    Vasu S, Yang JM, Hodges J, Abu-El-Haija MA, Adams DB, Balamurugan AN, Beilman GJ, Chinnakotla S, Conwell DL, Freeman ML, Gardner TB, Hatipoglu B, Kirchner V, Lara LF, Morgan KA, Nathan JD, Posselt A, Pruett TL, Schwarzenberg SJ, Singh VK, Wijkstrom M, Witkowski P, Naziruddin B, Bellin MD| | PubMed
  21. Preoperative ERCP has no impact on islet yield following total pancreatectomy and islet autotransplantation (TPIAT): Results from the Prospective Observational Study of TPIAT (POST) cohort.
    Trikudanathan G, Elmunzer BJ, Yang Y, Abu-El-Haija M, Adams D, Ahmad S, Balamurugan AN, Beilman GJ, Chinnakotla S, Conwell DL, Freeman ML, Gardner TB, Hatipoglu B, Hodges JS, Kirchner V, Lara LF, Long-Simpson L, Mitchell R, Morgan K, Nathan JD, Naziruddin B, Posselt A, Pruett TL, Schwarzenberg SJ, Singh VK, Smith K, Wijkstrom M, Witkowski P, Bellin MD| | PubMed
  22. COVID-19 and Abdominal Transplant: A Stepwise Approach to Practice During Pandemic Conditions.
    Syed SM, Gardner J, Roll G, Webber A, Mehta N, Shoji J, Adelmann D, Niemann C, Braun HJ, Mello A, Yao F, Posselt A, Kang SM, Hirose R, Roberts J, Feng S, Ascher N, Stock P, Freise C| | PubMed
  23. Phase 3 trial of human islet-after-kidney transplantation in type 1 diabetes.
    Markmann JF, Rickels MR, Eggerman TL, Bridges ND, Lafontant DE, Qidwai J, Foster E, Clarke WR, Kamoun M, Alejandro R, Bellin MD, Chaloner K, Czarniecki CW, Goldstein JS, Hering BJ, Hunsicker LG, Kaufman DB, Korsgren O, Larsen CP, Luo X, Naji A, Oberholzer J, Posselt AM, Ricordi C, Senior PA, Shapiro AMJ, Stock PG, Turgeon NA| | PubMed
  24. Ampullary stenosis and choledocholithiasis post Roux-En-Y gastric bypass: challenges of biliary access and intervention.
    Wisneski AD, Carter J, Nakakura EK, Posselt A, Rogers SJ, Cello JP, Arain M, Kirkwood KS, Hirose K, Stewart L, Corvera CU| | PubMed
  25. Long-term follow-up of beta cell replacement therapy in 10 HIV-infected patients with renal failure secondary to type 1 diabetes mellitus.
    Roll GR, Posselt AM, Freise J, Baird J, Syed S, Mo Kang S, Hirose R, Szot GL, Zarinsefat A, Feng S, Worner G, Sarwal M, Stock PG| | PubMed
  26. Obesity, transplantation, and bariatric surgery: An evolving solution for a growing epidemic.
    Diwan TS, Lee TC, Nagai S, Benedetti E, Posselt A, Bumgardner G, Noria S, Whitson BA, Ratner L, Mason D, Friedman J, Woodside KJ, Heimbach J| | PubMed
  27. Increases in PYY and uncoupling of bone turnover are associated with loss of bone mass after gastric bypass surgery.
    Kim TY, Shoback DM, Black DM, Rogers SJ, Stewart L, Carter JT, Posselt AM, King NJ, Schafer AL| | PubMed
  28. A Study on the Effect of Patient Characteristics, Geographical Utilization, and Patient Outcomes for Total Pancreatectomy Alone and Total Pancreatectomy With Islet Autotransplantation in Patients With Pancreatitis in the United States.
    Lara LF, Bellin MD, Ugbarugba E, Nathan JD, Witkowski P, Wijkstrom M, Steel JL, Smith KD, Singh VK, Schwarzenberg SJ, Pruett TL, Naziruddin B, Long-Simpson L, Kirchner VA, Gardner TB, Freeman ML, Dunn TB, Chinnakotla S, Beilman GJ, Adams DB, Morgan KA, Abu-El-Haija MA, Ahmad S, Posselt AM, Hughes MG, Conwell DL| | PubMed
  29. Outcomes of Sleeve Gastrectomy in Obese Liver Transplant Candidates.
    Sharpton SR, Terrault NA, Posselt AM| | PubMed
  30. Changes in Lean Mass, Absolute and Relative Muscle Strength, and Physical Performance After Gastric Bypass Surgery.
    Alba DL, Wu L, Cawthon PM, Mulligan K, Lang T, Patel S, King NJ, Carter JT, Rogers SJ, Posselt AM, Stewart L, Shoback DM, Schafer AL| | PubMed
  31. Oxygen Perfusion (Persufflation) of Human Pancreata Enhances Insulin Secretion and Attenuates Islet Proinflammatory Signaling.
    Kelly AC, Smith KE, Purvis WG, Min CG, Weber CS, Cooksey AM, Hasilo C, Paraskevas S, Suszynski TM, Weegman BP, Anderson MJ, Camacho LE, Harland RC, Loudovaris T, Jandova J, Molano DS, Price ND, Georgiev IG, Scott WE, Manas DMD, Shaw JAM, O'Gorman D, Kin T, McCarthy FM, Szot GL, Posselt AM, Stock PG, Karatzas T, Shapiro AMJ, Lynch RM, Limesand SW, Papas KK| | PubMed
  32. Effects of Gastric Bypass Surgery on Bone Mass and Microarchitecture Occur Early and Particularly Impact Postmenopausal Women.
    Schafer AL, Kazakia GJ, Vittinghoff E, Stewart L, Rogers SJ, Kim TY, Carter JT, Posselt AM, Pasco C, Shoback DM, Black DM| | PubMed
  33. Splenic Vein Thrombosis Following Pancreas Transplantation: Identification of Factors That Support Conservative Management.
    Harbell JW, Morgan T, Feldstein VA, Roll GR, Posselt A, Kang SM, Feng S, Hirose R, Freise CE, Stock P| | PubMed
  34. Bone Marrow Fat Changes After Gastric Bypass Surgery Are Associated With Loss of Bone Mass.
    Kim TY, Schwartz AV, Li X, Xu K, Black DM, Petrenko DM, Stewart L, Rogers SJ, Posselt AM, Carter JT, Shoback DM, Schafer AL| | PubMed
  35. Erratum. National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities. Diabetes 2016;65:3418-3428.
    Ricordi C, Goldstein JS, Balamurugan AN, Szot GL, Kin T, Liu C, Czarniecki CW, Barbaro B, Bridges ND, Cano J, Clarke WR, Eggerman TL, Hunsicker LG, Kaufman DB, Khan A, Lafontant DE, Linetsky E, Luo X, Markmann JF, Naji A, Korsgren O, Oberholzer J, Turgeon NA, Brandhorst D, Friberg AS, Lei J, Wang LJ, Wilhelm JJ, Willits J, Zhang X, Hering BJ, Posselt AM, Stock PG, Shapiro AMJ| | PubMed
  36. Correction: An intravascular bioartificial pancreas device (iBAP) with silicon nanopore membranes (SNM) for islet encapsulation under convective mass transport.
    Song S, Blaha C, Moses W, Park J, Wright N, Groszek J, Fissell W, Vartanian S, Posselt AM, Roy S| | PubMed
  37. Pancreas-After-Islet Transplantation in Nonuremic Type 1 Diabetes: A Strategy for Restoring Durable Insulin Independence.
    Wisel SA, Gardner JM, Roll GR, Harbell J, Freise CE, Feng S, Kang SM, Hirose R, Kaufman DB, Posselt AM, Stock PG| | PubMed
  38. Purified Human Pancreatic Islets, CIT Culture Media with Lisofylline or Exenatide.
    NIH CIT Consortium Chemistry Manufacturing Controls Monitoring Committee, Ansite J, Balamurugan AN, Barbaro B, Battle J, Brandhorst D, Cano J, Chen X, Deng S, Feddersen D, Friberg A, Gilmore T, Goldstein JS, Holbrook E, Khan A, Kin T, Lei J, Linetsky E, Liu C, Luo X, McElvaney K, Min Z, Moreno J, O'Gorman D, Papas KK, Putz G, Ricordi C, Szot G, Templeton T, Wang L, Wilhelm JJ, Willits J, Wilson T, Zhang X, NIH CIT Consortium, Avila J, Begley B, Cano J, Carpentier S, Holbrook E, Hutchinson J, Larsen CP, Moreno J, Sears M, Turgeon NA, Webster D, Deng S, Lei J, Markmann JF, Bridges ND, Czarniecki CW, Goldstein JS, Putz G, Templeton T, Wilson T, Eggerman TL, Al-Saden P, Battle J, Chen X, Hecyk A, Kissler H, Luo X, Molitch M, Monson N, Stuart E, Wallia A, Wang L, Wang S, Zhang X, Bigam D, Campbell P, Dinyari P, Kin T, Kneteman N, Lyon J, Malcolm A, O'Gorman D, Onderka C, Owen R, Pawlick R, Richer B, Rosichuk S, Sarman D, Schroeder A, Senior PA, Shapiro AMJ, Toth L, Toth V, Zhai W, Johnson K, McElroy J, Posselt AM, Ramos M, Rojas T, Stock PG, Szot G, Barbaro B, Martellotto J, Oberholzer J, Qi M, Wang Y, Bayman L, Chaloner K, Clarke W, Dillon JS, Diltz C, Doelle GC, Ecklund D, Feddersen D, Foster E, Hunsicker LG, Jasperson C, Lafontant DE, McElvaney K, Neill-Hudson T, Nollen D, Qidwai J, Riss H, Schwieger T, Willits J, Yankey J, Alejandro R, Corrales AC, Faradji R, Froud T, Garcia AA, Herrada E, Ichii H, Inverardi L, Kenyon N, Khan A, Linetsky E, Montelongo J, Peixoto E, Peterson K, Ricordi C, Szust J, Wang X, Abdulla MH, Ansite J, Balamurugan AN, Bellin MD, Brandenburg M, Gilmore T, Harmon JV, Hering BJ, Kandaswamy R, Loganathan G, Mueller K, Papas KK, Pedersen J, Wilhelm JJ, Witson J, Dalton-Bakes C, Fu H, Kamoun M, Kearns J, Li Y, Liu C, Luning-Prak E, Luo Y, Markmann E, Min Z, Naji A, Palanjian M, Rickels M, Shlansky-Goldberg R, Vivek K, Ziaie AS, Fernandez L, Kaufman DB, Zitur L, Brandhorst D, Friberg A, Korsgren O| | PubMed
  39. An intravascular bioartificial pancreas device (iBAP) with silicon nanopore membranes (SNM) for islet encapsulation under convective mass transport.
    Song S, Blaha C, Moses W, Park J, Wright N, Groszek J, Fissell W, Vartanian S, Posselt AM, Roy S| | PubMed
  40. Glucose-Stimulated Insulin Response of Silicon Nanopore-Immunoprotected Islets under Convective Transport.
    Song S, Yeung R, Park J, Posselt AM, Desai TA, Tang Q, Roy S| | PubMed
  41. A Single Perioperative Injection of Dexamethasone Decreases Nausea, Vomiting, and Pain after Laparoscopic Donor Nephrectomy.
    Yamanaga S, Posselt AM, Freise CE, Kobayashi T, Tavakol M, Kang SM| | PubMed
  42. National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities.
    Ricordi C, Goldstein JS, Balamurugan AN, Szot GL, Kin T, Liu C, Czarniecki CW, Barbaro B, Bridges ND, Cano J, Clarke WR, Eggerman TL, Hunsicker LG, Kaufman DB, Khan A, Lafontant DE, Linetsky E, Luo X, Markmann JF, Naji A, Korsgren O, Oberholzer J, Turgeon NA, Brandhorst D, Chen X, Friberg AS, Lei J, Wang LJ, Wilhelm JJ, Willits J, Zhang X, Hering BJ, Posselt AM, Stock PG, Shapiro AM, Chen X| | PubMed
  43. Abnormalities in biomarkers of mineral and bone metabolism in kidney donors.
    Kasiske BL, Kumar R, Kimmel PL, Pesavento TE, Kalil RS, Kraus ES, Rabb H, Posselt AM, Anderson-Haag TL, Steffes MW, Israni AK, Snyder JJ, Singh RJ, Weir MR| | PubMed
  44. Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia.
    Hering BJ, Clarke WR, Bridges ND, Eggerman TL, Alejandro R, Bellin MD, Chaloner K, Czarniecki CW, Goldstein JS, Hunsicker LG, Kaufman DB, Korsgren O, Larsen CP, Luo X, Markmann JF, Naji A, Oberholzer J, Posselt AM, Rickels MR, Ricordi C, Robien MA, Senior PA, Shapiro AM, Stock PG, Turgeon NA, Clinical Islet Transplantation Consortium| | PubMed
  45. Silicon nanopore membrane (SNM) for islet encapsulation and immunoisolation under convective transport.
    Song S, Faleo G, Yeung R, Kant R, Posselt AM, Desai TA, Tang Q, Roy S| | PubMed
  46. Effect of Immigration Status on Outcomes in Pediatric Kidney Transplant Recipients.
    McEnhill ME, Brennan JL, Winnicki E, Lee MM, Tavakol M, Posselt AM, Stock PG, Portale AA| | PubMed
  47. A Multicenter Study: North American Islet Donor Score in Donor Pancreas Selection for Human Islet Isolation for Transplantation.
    Wang LJ, Kin T, O'Gorman D, Shapiro AMJ, Naziruddin B, Takita M, Levy MF, Posselt AM, Szot GL, Savari O, Barbaro B, McGarrigle J, Yeh CC, Oberholzer J, Lei J, Chen T, Lian M, Markmann JF, Alvarez A, Linetsky E, Ricordi C, Balamurugan AN, Loganathan G, Wilhelm JJ, Hering BJ, Bottino R, Trucco M, Liu C, Min Z, Li Y, Naji A, Fernandez LA, Ziemelis M, Danobeitia JS, Millis JM, Witkowski P| | PubMed
  48. Under Utilization of Pancreas Transplants in Cystic Fibrosis Recipients in the United Network Organ Sharing (UNOS) Data 1987-2014.
    Usatin DJ, Perito ER, Posselt AM, Rosenthal P| | PubMed
  49. A Comparative Analysis of the Safety, Efficacy, and Cost of Islet Versus Pancreas Transplantation in Nonuremic Patients With Type 1 Diabetes.
    Moassesfar S, Masharani U, Frassetto LA, Szot GL, Tavakol M, Stock PG, Posselt AM| | PubMed
  50. Expanded indications for bariatric surgery: should patients on chronic steroids be offered bariatric procedures?
    Kaplan JA, Schecter SC, Rogers SJ, Lin MYC, Posselt AM, Carter JT| | PubMed
  51. Intestinal Calcium Absorption Decreases Dramatically After Gastric Bypass Surgery Despite Optimization of Vitamin D Status.
    Schafer AL, Weaver CM, Black DM, Wheeler AL, Chang H, Szefc GV, Stewart L, Rogers SJ, Carter JT, Posselt AM, Shoback DM, Sellmeyer DE| | PubMed
  52. Autologous islet transplantation with remote islet isolation after pancreas resection for chronic pancreatitis.
    Tai DS, Shen N, Szot GL, Posselt A, Feduska NJ, Habashy A, Clerkin B, Core E, Busuttil RW, Hines OJ, Reber HA, Lipshutz GS| | PubMed
  53. Changes in vertebral bone marrow fat and bone mass after gastric bypass surgery: A pilot study.
    Schafer AL, Li X, Schwartz AV, Tufts LS, Wheeler AL, Grunfeld C, Stewart L, Rogers SJ, Carter JT, Posselt AM, Black DM, Shoback DM| | PubMed
  54. Islet transplantation for Type 1 diabetes: where are we now?
    Ahearn AJ, Parekh JR, Posselt AM| | PubMed
  55. Islet product characteristics and factors related to successful human islet transplantation from the Collaborative Islet Transplant Registry (CITR) 1999-2010.
    Balamurugan AN, Naziruddin B, Lockridge A, Tiwari M, Loganathan G, Takita M, Matsumoto S, Papas K, Trieger M, Rainis H, Kin T, Kay TW, Wease S, Messinger S, Ricordi C, Alejandro R, Markmann J, Kerr-Conti J, Rickels MR, Liu C, Zhang X, Witkowski P, Posselt A, Maffi P, Secchi A, Berney T, O'Connell PJ, Hering BJ, Barton FB| | PubMed
  56. Human islet viability and function is maintained during high-density shipment in silicone rubber membrane vessels.
    Kitzmann JP, Pepper AR, Gala-Lopez B, Pawlick R, Kin T, O'Gorman D, Mueller KR, Gruessner AC, Avgoustiniatos ES, Karatzas T, Szot GL, Posselt AM, Stock PG, Wilson JR, Shapiro AM, Papas KK| | PubMed
  57. Predictors of hospital stay following laparoscopic gastric bypass: analysis of 9,593 patients from the National Surgical Quality Improvement Program.
    Carter J, Elliott S, Kaplan J, Lin M, Posselt A, Rogers S| | PubMed
  58. Combined pancreatic islet and kidney transplantation in a child with unstable type 1 diabetes and end-stage renal disease.
    Benedict KA, Moassesfar S, Adi S, Gitelman SE, Brennan JL, McEnhill M, Stock PG, Portale AA, Posselt AM| | PubMed
  59. Laparoscopic sleeve gastrectomy is safe and efficacious for pretransplant candidates.
    Lin MY, Tavakol MM, Sarin A, Amirkiai SM, Rogers SJ, Carter JT, Posselt AM| | PubMed
  60. Improvement in outcomes of clinical islet transplantation: 1999-2010.
    Barton FB, Rickels MR, Alejandro R, Hering BJ, Wease S, Naziruddin B, Oberholzer J, Odorico JS, Garfinkel MR, Levy M, Pattou F, Berney T, Secchi A, Messinger S, Senior PA, Maffi P, Posselt A, Stock PG, Kaufman DB, Luo X, Kandeel F, Cagliero E, Turgeon NA, Witkowski P, Naji A, O'Connell PJ, Greenbaum C, Kudva YC, Brayman KL, Aull MJ, Larsen C, Kay TW, Fernandez LA, Vantyghem MC, Bellin M, Shapiro AM| | PubMed
  61. Safety and feasibility of sleeve gastrectomy in morbidly obese patients following liver transplantation.
    Lin MY, Tavakol MM, Sarin A, Amirkiai SM, Rogers SJ, Carter JT, Posselt AM| | PubMed
  62. Islet Transplantation & β-Cell Replacement Therapies for Diabetes.
    Berney T, Korsgren O, Posselt A, Pileggi A| | PubMed
  63. Experience with laparoscopic donor nephrectomy among more than 1000 cases: low complication rates, despite more challenging cases.
    Ahearn AJ, Posselt AM, Kang SM, Roberts JP, Freise CE| | PubMed
  64. Early and late abdominal bleeding after Roux-en-Y gastric bypass: sources and tailored therapeutic strategies.
    Rabl C, Peeva S, Prado K, James AW, Rogers SJ, Posselt A, Campos GM| | PubMed
  65. Islet transplantation in type 1 diabetic patients using calcineurin inhibitor-free immunosuppressive protocols based on T-cell adhesion or costimulation blockade.
    Posselt AM, Szot GL, Frassetto LA, Masharani U, Tavakol M, Amin R, McElroy J, Ramos MD, Kerlan RK, Fong L, Vincenti F, Bluestone JA, Stock PG| | PubMed
  66. Islet transplantation in type 1 diabetics using an immunosuppressive protocol based on the anti-LFA-1 antibody efalizumab.
    Posselt AM, Bellin MD, Tavakol M, Szot GL, Frassetto LA, Masharani U, Kerlan RK, Fong L, Vincenti FG, Hering BJ, Bluestone JA, Stock PG| | PubMed
  67. Clinical islet transplantation at the University of California, San Francisco.
    Posselt AM, Szot GL, Frassetto LA, Masharani U, Stock PG| | PubMed
  68. Successful clinical islet isolation using a GMP-manufactured collagenase and neutral protease.
    Szot GL, Lee MR, Tavakol MM, Lang J, Dekovic F, Kerlan RK, Stock PG, Posselt AM| | PubMed
  69. Portomesenteric venous thrombosis after laparoscopic surgery: a systematic literature review.
    James AW, Rabl C, Westphalen AC, Fogarty PF, Posselt AM, Campos GM| | PubMed
  70. Long-term renal function and cardiovascular disease risk in obese kidney donors.
    Tavakol MM, Vincenti FG, Assadi H, Frederick MJ, Tomlanovich SJ, Roberts JP, Posselt AM| | PubMed
  71. Factors associated with weight loss after gastric bypass.
    Campos GM, Rabl C, Mulligan K, Posselt A, Rogers SJ, Westphalen AC, Lin F, Vittinghoff E| | PubMed
  72. A clinical scoring system for predicting nonalcoholic steatohepatitis in morbidly obese patients.
    Campos GM, Bambha K, Vittinghoff E, Rabl C, Posselt AM, Ciovica R, Tiwari U, Ferrel L, Pabst M, Bass NM, Merriman RB| | PubMed
  73. Laparoscopic bariatric surgery improves candidacy in morbidly obese patients awaiting transplantation.
    Takata MC, Campos GM, Ciovica R, Rabl C, Rogers SJ, Cello JP, Ascher NL, Posselt AM| | PubMed
  74. Human albumin preserves islet mass and function better than whole serum during pretransplantation islet culture.
    Lee RH, Carter J, Szot GL, Posselt A, Stock P| | PubMed
  75. The impact of roux limb length on weight loss after gastric bypass.
    Ciovica R, Takata M, Vittinghoff E, Lin F, Posselt AM, Rabl C, Stein HJ, Campos GM| | PubMed
  76. Catheter-directed therapy for DVT after pancreas transplantation.
    Mahanty HD, Posselt AM, Lipshutz GS, Schneider DB, Freise CE| | PubMed
  77. Spectrum and risk factors of complications after gastric bypass.
    Campos GM, Ciovica R, Rogers SJ, Posselt AM, Vittinghoff E, Takata M, Cello JP| | PubMed
  78. Predictors, treatment, and outcomes of gastrojejunostomy stricture after gastric bypass for morbid obesity.
    Takata MC, Ciovica R, Cello JP, Posselt AM, Rogers SJ, Campos GM| | PubMed
  79. Routine upper GI series after gastric bypass does not reliably identify anastomotic leaks or predict stricture formation.
    Carter JT, Tafreshian S, Campos GM, Tiwari U, Herbella F, Cello JP, Patti MG, Rogers SJ, Posselt AM| | PubMed
  80. Propylthiouracil-associated liver failure presenting as probable autoimmune hepatitis in a child with Graves' disease.
    Sipe WE, Su M, Posselt A, Kim GE, Quiros JA, Rosenthal P| | PubMed
  81. Antibody-mediated rejection of a pancreas allograft.
    Melcher ML, Olson JL, Baxter-Lowe LA, Stock PG, Posselt AM| | PubMed
  82. Pretransplant islet culture: a comparison of four serum-free media using a murine model of islet transplantation.
    Carter J, Karmiol S, Nagy M, McElreath R, Calloway C, Motley A, Neill A, Jang HJ, Posselt A, Stock P| | PubMed
  83. More than 500 consecutive laparoscopic donor nephrectomies without conversion or repeated surgery.
    Melcher ML, Carter JT, Posselt A, Duh QY, Stoller M, Freise CE, Kang SM| | PubMed
  84. Laparoscopic procurement of kidneys with multiple renal arteries is associated with increased ureteral complications in the recipient.
    Carter JT, Freise CE, McTaggart RA, Mahanty HD, Kang SM, Chan SH, Feng S, Roberts JP, Posselt AM| | PubMed
  85. BKV in simultaneous pancreas-kidney transplant recipients: a leading cause of renal graft loss in first 2 years post-transplant.
    Lipshutz GS, Mahanty H, Feng S, Hirose R, Stock PG, Kang SM, Posselt AM, Freise CE| | PubMed
  86. Laparoscopic right donor nephrectomy: a large single-center experience.
    Posselt AM, Mahanty H, Kang SM, Stoller ML, Meng MV, Roberts JP, Freise CE| | PubMed
  87. Experience with steroid-free maintenance immunosuppression in simultaneous pancreas-kidney transplantation.
    Freise CE, Kang SM, Feng S, Posselt A, Hirose K, Hirose R, Stock P| | PubMed
  88. Congenital cleft spleen with CT scan appearance of high-grade splenic laceration after blunt abdominal trauma.
    Brennan TV, Lipshutz GS, Posselt AM, Horn JK| | PubMed
  89. CD69 expression on peripheral CD8 T cells correlates with acute rejection in renal transplant recipients.
    Posselt AM, Vincenti F, Bedolli M, Lantz M, Roberts JP, Hirose R| | PubMed
  90. Longevity of 2328 chairside Cerec inlays and onlays.
    Posselt A, Kerschbaum T| | PubMed
  91. Intraportal delivery of immunosuppression to intrahepatic islet allograft recipients.
    Wang X, Alfrey EJ, Posselt A, Tafra L, Alak AM, Dafoe DC| | PubMed
  92. Prolongation of survival of donor-strain islet xenografts (rat-->mouse) by intrathymic inoculation of xenogeneic islet and bone marrow cells.
    Mayo GL, Posselt AM, Barker CF, Rostami S, Mayo SP, Campos L, Naji A| | PubMed
  93. Intrathymic transplantation promotes survival of islet xenografts (rat-->mouse).
    Mayo GL, Posselt AM, Campos L, Noorchashm N, Barker CF, Naji A| | PubMed
  94. The failure of intrathymic transplantation of nonimmunogenic islet allografts to promote induction of donor-specific unresponsiveness.
    Campos L, Posselt AM, Deli BC, Mayo GL, Pete K, Barker CF, Naji A| | PubMed
  95. Examination of the mechanisms responsible for tolerance induction after intrathymic inoculation of allogeneic bone marrow.
    Odorico JS, O'Connor T, Campos L, Barker CF, Posselt AM, Naji A| | PubMed
  96. Promotion of rat cardiac allograft survival by intrathymic inoculation of donor splenocytes.
    Odorico JS, Posselt AM, Naji A, Markmann JF, Barker CF| | PubMed
  97. Prolonged survival of rat orthotopic liver allografts after intrathymic inoculation of donor-strain cells.
    Campos L, Alfrey EJ, Posselt AM, Odorico JS, Barker CF, Naji A| | PubMed
  98. Intrathymic inoculation of donor cells promotes survival of rat orthotopic liver allografts.
    Campos L, Alfrey EJ, Posselt AM, Odorico JS, Naji A, Barker CF| | PubMed
  99. Intrathymic inoculation of islets at birth prevents autoimmune diabetes and pancreatic insulitis in the BB rat.
    Posselt AM, Barker CF, Friedman AL, Koeberlein B, Tomaszewski JE, Naji A| | PubMed
  100. Prolonged survival of rat cardiac allografts after intrathymic inoculation of donor thymocytes.
    Odorico JS, Barker CF, Markmann JF, Posselt AM, Naji A| | PubMed
  101. Intrathymic transplantation as a model for tolerance.
    Barker CF, Posselt AM, Odorico JS, Markmann JF, Naji A| | PubMed
  102. Prolongation of rat pancreatic islet allograft survival by anti-CD2 monoclonal antibody treatment.
    Roark JH, Posselt AM, Campos L, Kim J, Chavin KD, Bromberg JS, Barker CF, Naji A| | PubMed
  103. Pioneering work in immune tolerance.
    Naji A, Posselt AM, Barker CF| | PubMed
  104. Microchimerism of the thymus and graft acceptance.
    Posselt AM, Naji A, Barker CF| | PubMed
  105. Induction of donor-specific tolerance to rat cardiac allografts by intrathymic inoculation of bone marrow.
    Odorico JS, Barker CF, Posselt AM, Naji A| | PubMed
  106. Promotion of pancreatic islet allograft survival by intrathymic transplantation of bone marrow.
    Posselt AM, Odorico JS, Barker CF, Naji A| | PubMed
  107. Successful islet transplantation in the thymus of spontaneously diabetic BB rats.
    Posselt AM, Barker CF, Markmann JF, Roark JH, Naji A| | PubMed
  108. Prevention of autoimmune diabetes in the BB rat by intrathymic islet transplantation at birth.
    Posselt AM, Barker CF, Friedman AL, Naji A| | PubMed
  109. Intraportal FK 506 improves intrahepatic islet allograft survival.
    Wang X, Berezniak R, Tafra L, Posselt A, Barker CF, Dafoe DC| | PubMed
  110. Intrathymic islet transplantation in the spontaneously diabetic BB rat.
    Posselt AM, Naji A, Roark JH, Markmann JF, Barker CF| | PubMed
  111. Major-histocompatibility-complex restricted and nonrestricted autoimmune effector mechanisms in BB rats.
    Markmann JF, Posselt AM, Bassiri H, Brayman KL, Woehrle M, Hickey WF, Silvers WK, Barker CF, Naji A| | PubMed
  112. Studies of privileged sites and islet transplantation.
    Barker CF, Markmann JF, Posselt AM, Naji A| | PubMed
  113. Selective T-cell depletion of recipients in allogeneic small bowel transplantation (SBT) in the rat.
    Deaton DH, Posselt AM, Naji A, Barker CF| | PubMed
  114. Induction of donor-specific unresponsiveness by intrathymic islet transplantation.
    Posselt AM, Barker CF, Tomaszewski JE, Markmann JF, Choti MA, Naji A| | PubMed
  115. Immunologic consequences of islet MHC antigen modulation in autoimmune diabetes.
    Markmann JF, Posselt AM, Levy M, Naji A, Barker CF| | PubMed
  116. The effect of islet cell culture in vitro at 24 degrees C on graft survival and MHC antigen expression.
    Markmann JF, Tomaszewski J, Posselt AM, Levy MM, Woehrle M, Barker CF, Naji A| | PubMed
  117. Suppression of carbon monoxide excretion rate by tin protoporphyrin.
    Posselt AM, Kwong LK, Vreman HJ, Stevenson DK| | PubMed
  118. Effect of tin protoporphyrin on the excretion rate of carbon monoxide in newborn rats after hematoma formation.
    Posselt AM, Cowan BE, Kwong LK, Vreman HJ, Stevenson DK| | PubMed