Biography
In addition to caring for patients, Posselt conducts research on pancreatic islet cell transplantation, a procedure that can allow people with type 1 diabetes to discontinue insulin therapy. He also investigates mechanisms by which a transplant recipient's body rejects or tolerates tissue from a donor who isn't genetically identical, and he studies the metabolic and biochemical consequences of bariatric surgery.
Posselt earned his medical degree and a doctorate in immunology from the University of Pennsylvania. He completed residencies in internal medicine and general surgery as well as a transplant fellowship at UCSF, before joining the staff in 2003.
Posselt is a member of several professional and honorary societies, and has given presentations on transplant issues related to patient care and research. At UCSF, he supervises residents and fellows in transplant services and general surgery.
Videos
Education
Institution | Degree | Dept or School | End Date |
---|---|---|---|
University of Pennsylvania | PhD | Immunology | 1993 |
University of Pennsylvania | M.D. | School of Medicine | 1993 |
University of California, San Francisco | Residency | Internal Medicine |
Board Certifications
- American Board of Internal Medicine, 1996
- American Board of Surgery, 2002
Clinical Expertise
Bariatric Surgery (Laparoscopic and Open)
Bile Duct Injuries
Bile Duct Strictures
Choledochal Cyst Disease
End-Stage Kidney Disease
Fulminant Hepatic Failure
Hepatitis B
Hepatitis C
Hepatocellular Carcinoma (Primary Liver Cancer)
Kidney Transplantation
Laparoscopic Donor Nephrectomy
Liver Cysts
Liver Transplantation
Nonalcoholic Fatty Liver Disease
Pancreas Transplantation
Pediatric Liver Transplantation
Pediatric Kidney Transplantation
Portal Hypertension
Islet Cell Transplantation
Autologous Islet Cell Transplantation
Program Affiliations
Pancreatic Islet Transplantation Program
Bariatric Surgery Center
ABO-Incompatible Kidney Transplant Program
In the News
Grants and Funding
- Vertical Sleeve Gastrectomy for Treatment of NASH: a pilot randomized control | NIH | 2021-07-14 - 2024-05-31 | Role: Co-Principal Investigator
- Treatment of Type I Diabetes by Islet Transplantation into the Gastric Submucosa | NIH | 2014-05-01 - 2021-04-30 | Role: Principal Investigator
- "Advancing Islet Transplant for Type 1 Diabetes Care" | NIH | 2009-09-30 - 2013-07-31 | Role: Principal Investigator
- Effect of Obesity on Long-Term Clinical Outcomes after Kidney Donation | NIH | 2009-09-21 - 2012-06-30 | Role: Principal Investigator
Research Interests
- Transplantation of pancreatic islets as treatment for type 1 diabetes mellitus
- Assessment of long-term clinical outcomes in kidney donors
- Metabolic and biochemical consequences of bariatric surgery
- Clinical outcomes of bariatric surgery in patients with end-stage kidney or liver disease
Publications
- A Single Perioperative Injection of Dexamethasone Decreases Nausea, Vomiting, and Pain after Laparoscopic Donor Nephrectomy.| | PubMed
- National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities.| | PubMed
- Abnormalities in biomarkers of mineral and bone metabolism in kidney donors.| | PubMed
- Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia.| | PubMed
- Silicon nanopore membrane (SNM) for islet encapsulation and immunoisolation under convective transport.| | PubMed
- Effect of Immigration Status on Outcomes in Pediatric Kidney Transplant Recipients.| | PubMed
- A Multicenter Study: North American Islet Donor Score in Donor Pancreas Selection for Human Islet Isolation for Transplantation.| | PubMed
- Under Utilization of Pancreas Transplants in Cystic Fibrosis Recipients in the United Network Organ Sharing (UNOS) Data 1987-2014.| | PubMed
- A Comparative Analysis of the Safety, Efficacy, and Cost of Islet Versus Pancreas Transplantation in Nonuremic Patients With Type 1 Diabetes.| | PubMed
- Expanded indications for bariatric surgery: should patients on chronic steroids be offered bariatric procedures?| | PubMed